Publication Beamlines Strategic Pillar
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] CMCF-BM, CMCF-ID Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Chung, Ivy Yeuk Wah; Li, Lei; Cygler, Miroslaw (2021). Legionella effector LegA15/AnkH contains an unrecognized cysteine protease-like domain and displays structural similarity to LegA3/AnkD, but differs in host cell localization. Acta Crystallographica Section D: Structural Biology 77(12) . 10.1107/s2059798321010469. [PDB: 7kj6] CMCF-BM Health
Chung, Ivy Yeuk Wah; Cygler, Miroslaw (2022). Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system. Acta Crystallographica Section F:Structural Biology Communications 78(7) , 276-280. 10.1107/s2053230x22006604. [PDB: 7ups] CMCF-BM Health
Chen, Sizhu Amelia; Arutyunova, Elena; Lu, Jimmy; Khan, Muhammad Bashir; Rut, Wioletta et al. (2023). SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. ACS Central Science 9(4) , 696-708. 10.1021/acscentsci.3c00054. [PDB: 8djj, 8dk8, 8dkz] CMCF-BM Health
Caveney, N. A.; Serapio-Palacios, A.; Woodward, S. E.; Bozorgmehr, T.; Caballero, G. et al. (2021). Structural and Cellular Insights into the l , d -Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrobial Agents and Chemotherapy 65(2) . 10.1128/aac.01592-20. [PDB: 7kgm] CMCF-BM Health
Callahan, Alex J.; Gandhesiri, Satish; Travaline, Tara L.; Lozano Salazar, Lia; Hanna, Stephanie et al. (2023). Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display. Environmental Science and Technology . 10.26434/chemrxiv-2023-x86xp. [PDB: 8f16, 8f17] CMCF-BM Health
Bon, Christopher G.; Grigg, Jason C.; Lee, Jaeyong; Robb, Craig S.; Caveney, Nathanael A. et al. (2024). Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. Journal of Structural Biology 216(2) , 108086. 10.1016/j.jsb.2024.108086. [PDB: 8vbt, 8vbv, 8vbw] CMCF-BM Health
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Bai, Bing; Belovodskiy, Alexandr; Hena, Mostofa; Kandadai, Appan Srinivas; Joyce, Michael A. et al. (2021). Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability. Journal of Medicinal Chemistry 65(4) . 10.1021/acs.jmedchem.1c00616. CMCF-BM Health
Ali, Mohamed G.; Wahba, Haytham M.; Igelmann, Sebastian; Cyr, Normand; Ferbeyre, Gerardo et al. (2024). Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy . 10.1080/15548627.2024.2353443. [PDB: 8t33, 8t4t] CMCF-BM, CMCF-ID Health
Tyvanchuk, Yuriy B.; Fecica, Matthew; Garcia, Griheydi; Mar, Arthur; Oliynyk, Anton O. et al. (2021). Ternary Rare-Earth-Metal Nickel Indides RE23Ni7In4 (RE = Gd, Tb, Dy) with Yb23Cu7Mg4-Type Structure. Inorganic Chemistry 60(23) , 17900-17910. 10.1021/acs.inorgchem.1c02486. CMCF-BM Environment
Shrimpton, Heather K.; Ptacek, Carol J.; Blowes, David W. (2024). Selenite Stable Isotope Fractionation during Abiotic Reduction by Sodium Sulfide. Environmental Science and Technology . 10.1021/acs.est.4c03607. CMCF-BM Environment
Schoepfer, Valerie A.; Lum, Jullieta E.; Lindsay, Matthew B. J. (2021). Molybdenum(VI) Sequestration Mechanisms During Iron(II)-Induced Ferrihydrite Transformation. ACS Earth and Space Chemistry 5(8) , 2094-2104. 10.1021/acsearthspacechem.1c00152. BIOXAS-MAIN, CMCF-BM Environment