Publication Beamlines Strategic Pillar
Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. [PDB: 8cyu, 8cyz, 8sxr] CMCF-BM Health
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Navas, Laura E.; Zahn, Michael; Bajwa, Harbir; Grigg, Jason C.; Wolf, Megan E. et al. (2022). Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. Journal of Biological Chemistry 298(5) , 101871. 10.1016/j.jbc.2022.101871. [PDB: 7q2a] CMCF-BM Health
Nasseri, Seyed Amirhossein; Lazarski, Aleksander C.; Lemmer, Imke L.; Zhang, Chloe Y.; Brencher, Eva et al. (2024). An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature . 10.1038/s41586-024-07574-y. [PDB: 8tdi] CMCF-BM Health
Muna, Tasneem Hassan; Rutbeek, Nicole R; Horne, Julia; Lao, Ying W; Krokhin, Oleg V et al. (2024). The phage protein paratox is a multifunctional metabolic regulator of Streptococcus. Nucleic Acids Research . 10.1093/nar/gkae1200. [PDB: 8vsq] CMCF-BM Health
Mothersole, Robert G.; Kolesnikov, Maxim; Chan, Anson C. K.; Oduro, Emmanuella; Murphy, Michael E. P. et al. (2022). Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry 61(13) , 1378-1391. 10.1021/acs.biochem.2c00197. [PDB: 8d27] CMCF-BM Health
Miron, Caitlin E.; Staalduinen, Laura; Rangaswamy, Alana M.; Chen, Mickey; Liang, Yushi et al. (2020). Going Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution‐ and Solid‐State Investigations.. Angewandte Chemie - International Edition 60(5) . 10.1002/anie.202012520. [PDB: 6xcl] CMCF-BM Health
Miersch, Shane; Li, Zhijie; Saberianfar, Reza; Ustav, Mart; Case, James Brett et al. (2020). Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations. Vibrational Spectroscopy . 10.1101/2020.10.31.362848. [PDB: 7klg, 7klh] CMCF-BM Health
McLeod, Matthew J.; Tran, Norman; McCluskey, Gregory D.; Gillis, Tom D.; Bearne, Stephen L. et al. (2023). A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate. Protein Science 32(6) . 10.1002/pro.4648. [PDB: 8fv6, 8fv7, 8fv8, 8fv9, 8fva, 8fvb] CMCF-BM Health
McLeod, Matthew J.; Holyoak, Todd (2023). Biochemical, structural, and kinetic characterization of PPi‐dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii. Proteins: Structure. Function and Bioinformatics . 10.1002/prot.26513. [PDB: 8e1u] CMCF-BM Health
McGregor, Alexandra K.; Chan, Anson C.K.; Schroeder, Megan D.; Do, Long T.M.; Saini, Gurpreet et al. (2023). A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin. Journal of Biological Chemistry 299(7) , 104902. 10.1016/j.jbc.2023.104902. [PDB: 8g64] CMCF-BM Health
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] CMCF-BM, CMCF-ID Health
Majdi Yazdi, Mohadeseh; Saran, Sagar; Mrozowich, Tyler; Lehnert, Cheyanne; Patel, Trushar R. et al. (2020). Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase. Journal of Structural Biology 209(1) . 10.1016/j.jsb.2019.107409. [PDB: 6tzu, 6u01] CMCF-BM, CMCF-ID Health
Mabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Leung, Elisa; Chuang, Stephanie H.W. et al. (2022). Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure . 10.1016/j.str.2022.12.002. [PDB: 7uvm, 7uvn, 7uvr, 7uvu, 7uw0] CMCF-BM Health