Publication Beamlines Strategic Pillar
Sharon, Itai; McKay, Geoffrey A.; Nguyen, Dao; Schmeing, T. Martin (2023). Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proceedings of the National Academy of Sciences of the United States of America 120(8) . 10.1073/pnas.2216547120. CMCF-BM Health
Sharon, Itai; Schmeing, T. Martin (2023). Bioinformatics of cyanophycin metabolism genes and characterization of promiscuous isoaspartyl dipeptidases that catalyze the final step of cyanophycin degradation. Scientific Reports 13(1) . 10.1038/s41598-023-34587-w. CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Shen, Yi; Wen, Yurong; Sposini, Silvia; Vishwanath, Anjali Amrapali; Abdelfattah, Ahmed S. et al. (2023). Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sensors . 10.1021/acssensors.3c00484. [PDB: 7yv3, 7yv5] CMCF-ID Health
Shin, Jeonghee; Park, Sehee; Trinh, Tung X.; Kwon, Sook Jin; Bae, Jiwon et al. (2021). Scanning transmission X-ray microscopy study of subcellular granules in human platelets at the carbon K- and calcium L2,3-edges. Platelets 33(4) , 1-8. 10.1080/09537104.2021.1981846. SM Health
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] CMCF-BM Health
Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. [PDB: 6m91, 6m92, 6m93, 6m94] CMCF-ID Health
Sirovica, Slobodan; Solheim, Johanne H.; Skoda, Maximilian W. A.; Hirschmugl, Carol J.; Mattson, Eric C. et al. (2020). Origin of micro-scale heterogeneity in polymerisation of photo-activated resin composites. Nature Communications 11(1) . 10.1038/s41467-020-15669-z. MID-IR Health
Sishi, Zhu; Bahig, Jumanah; Kalugin, Denis; Shoker, Ahmed; Zhu, Ning et al. (2023). Influence of clinical hemodialysis membrane morphology and chemistry on protein adsorption and inflammatory biomarkers released: In-situ synchrotron imaging, clinical and computational studies. Biomedical Engineering Advances 5, 100070. 10.1016/j.bea.2022.100070. BMIT-BM Health
Smith, Bryan D.; Kaufman, Michael D.; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B. et al. (2019). Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants. Cancer Cell 35(5) , 738-751.e9. 10.1016/j.ccell.2019.04.006. [PDB: 6mob] CMCF-ID Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] CMCF-BM, CMCF-ID Health
Sokaribo, Akosiererem; Novakovski, Brian A.A.; Cotelesage, Julien; White, Aaron P.; Sanders, David et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517. [PDB: 6v2l, 6v2m, 6v2n] CMCF-BM, CMCF-ID Health
Soltan, Nikoo; Kawalilak, Chantal E.; Cooper, David M.; Kontulainen, Saija A.; Johnston, James D. et al. (2019). Cortical porosity assessment in the distal radius: A comparison of HR-pQCT measures with Synchrotron-Radiation micro-CT-based measures. Bone 120, 439-445. 10.1016/j.bone.2018.12.008. BMIT-ID Health
Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] CMCF-ID Health
Stachel, Shawn J.; Ginnetti, Anthony T.; Johnson, Scott A.; Cramer, Paige; Wang, Yi et al. (2020). Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic and Medicinal Chemistry Letters 30(17) , 127403. 10.1016/j.bmcl.2020.127403. [PDB: 6x3l, 6x48] CMCF-ID Health