Rathinaswamy, Manoj Kumar (2021). Molecular basis for the regulation of phosphoinositide 3-kinase γ (PI3Kγ). Supervisor: Burke, John. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/13168. |
CMCF-ID |
Doctoral Thesis |
Health |
Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Rasool, S.; Veyron, S.; Trempe, J.F. (2021). Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 phosphorylated at Ser205 in complex with ADP analog. Protein Data Bank: 7mp9. |
CMCF-ID |
PDB Deposition |
Health |
Rasool, S.; Veyron, S.; Trempe, J.F. (2021). Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 in the non-phosphorylated state. Protein Data Bank: 7mp8. |
CMCF-ID |
PDB Deposition |
Health |
Rasool, Shafqat; Veyron, Simon; Soya, Naoto; Eldeeb, Mohamed A.; Lukacs, Gergely L. et al. (2022). Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Molecular Cell 82(1) , 44-59. 10.1016/j.molcel.2021.11.012. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ramasubramanian, Anusuya; Tennyson, Rachel; Magnay, Maureen; Kathuria, Sagar; Travaline, Tara et al. (2020). Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies 9(4) , 62. 10.3390/antib9040062. [PDB: 7jkb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Raman, S.; Bosch, A.; Fransson, J.; Julien, J.P. (2022). Structure of Human Leukaemia Inhibitory Factor with Fab MSC1. Protein Data Bank: 7n0a. |
CMCF-ID |
PDB Deposition |
Health |
Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 7 CRD in complex with F7.B Fab. Protein Data Bank: 6o3a. |
CMCF-ID |
PDB Deposition |
Health |
Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 5 CRD in complex with F2.I Fab. Protein Data Bank: 6o39. |
CMCF-ID |
PDB Deposition |
Health |
Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Radka, Christopher D.; Labiuk, Shaunivan L.; DeLucas, Lawrence J.; Aller, Stephen G. (2019). Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. Acta Crystallographica Section D: Structural Biology 75(9) . 10.1107/s2059798319010866. [PDB: 6q1d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Qiu, Y. (2025). Crystal structure of anti-abTCR NANOBODY VHH. Protein Data Bank: 9bdo. |
CMCF-ID |
PDB Deposition |
Health |
Qian, S.; Li, H.; Fan, X.; Tian, X.; Li, J. et al. (2022). Structure of a triple-helix region of human collagen type III. Protein Data Bank: 7xan. |
CMCF-ID |
PDB Deposition |
Health |