Publication Beamlines Strategic Pillar
Stogios, P.J.; Skarina, T.; Arnal, G.; Brumer, H.; Savchenko, A. et al. (2019). Crystal structure of Niastella koreensis GH74 (NkGH74) enzyme. Protein Data Bank: 6p2l. CMCF-ID Health
Stirling, Alexander J.; Gilbert, Stephanie E.; Conner, Megan; Mallette, Evan; Kimber, Matthew S. et al. (2020). A Key Glycine in Bacterial Steroid-Degrading Acyl-CoA Dehydrogenases Allows Flavin-Ring Repositioning and Modulates Substrate Side Chain Specificity. Biochemistry 59(42) , 4081-4092. 10.1021/acs.biochem.0c00568. [PDB: 6wy8, 6wy9] CMCF-ID Health
Stachel, Shawn J.; Ginnetti, Anthony T.; Johnson, Scott A.; Cramer, Paige; Wang, Yi et al. (2020). Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic and Medicinal Chemistry Letters 30(17) , 127403. 10.1016/j.bmcl.2020.127403. [PDB: 6x3l, 6x48] CMCF-ID Health
Spurlino, J.C.; Milligan, C. (2025). An RORgt Inverse agonist for treatment of Psoriasis. Protein Data Bank: 9n9l. CMCF-ID Health
Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] CMCF-ID Health
Sokaribo, Akosiererem; Novakovski, Brian A.A.; Cotelesage, Julien; White, Aaron P.; Sanders, David et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517. [PDB: 6v2l, 6v2m, 6v2n] CMCF-BM, CMCF-ID Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] CMCF-BM, CMCF-ID Health
Smith, Bryan D.; Kaufman, Michael D.; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B. et al. (2019). Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants. Cancer Cell 35(5) , 738-751.e9. 10.1016/j.ccell.2019.04.006. [PDB: 6mob] CMCF-ID Health
Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML00789344 adduct bound to SAE. Protein Data Bank: 6xoh. CMCF-ID Health
Sintchak, M.; Lane, W.; Bump, N. (2021). Structure of SUMO1-ML786519 adduct bound to SAE. Protein Data Bank: 6xog. CMCF-ID Health
Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. [PDB: 6m91, 6m92, 6m93, 6m94] CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Lee, S.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex. Protein Data Bank: 6m93. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-2663 ternary complex. Protein Data Bank: 6m92. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex. Protein Data Bank: 6m94. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-103094 ternary complex. Protein Data Bank: 6m91. CMCF-ID Health