Publication Beamlines Strategic Pillar
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] CMCF-ID Health
Keylor, Mitchell H.; Gulati, Anmol; Kattar, Solomon D.; Johnson, Rebecca E.; Chau, Ryan W. et al. (2021). Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. Journal of Medicinal Chemistry 65(1) , 838-856. 10.1021/acs.jmedchem.1c01968. [PDB: 7suh] CMCF-ID Health
Khan, Nimra; Pelletier, Dylan; Veyron, Simon; Croteau, Nathalie; Ichikawa, Muneyoshi et al. (2019). Crystal structure of human PACRG in complex with MEIG1. FEMS Microbiology Ecology . 10.1101/783373. [PDB: 6ndu, 6ucc] CMCF-ID Health
Kim, Hyeong Jin; Black, Mazzen; Edwards, Ross A.; Peillard-Fiorente, Flora; Panigrahi, Rashmi et al. (2022). Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones. Nature Communications 13(1) . 10.1038/s41467-022-34875-5. [PDB: 7rgt] CMCF-ID Health
Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph et al. (2025). Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis. Journal of Medicinal Chemistry 68(8) , 8713-8728. 10.1021/acs.jmedchem.5c00390. [PDB: 9n9l] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health
Kozlov, Guennadi; Mattijssen, Sandy; Jiang, Jianning; Nyandwi, Samuel; Sprules, Tara et al. (2022). Structural basis of 3′-end poly(A) RNA recognition by LARP1. Nucleic Acids Research 50(16) , 9534-9547. 10.1093/nar/gkac696. [PDB: 7soo, 7sop] CMCF-ID Health
Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] CMCF-ID Health
Kuduk, Scott D.; Stoops, Bart; Alexander, Richard; Lam, Angela M.; Espiritu, Christine et al. (2021). Identification of a new class of HBV capsid assembly modulator. Bioorganic and Medicinal Chemistry Letters 39, 127848. 10.1016/j.bmcl.2021.127848. [PDB: 7k5m] CMCF-ID Health
Kumar, Amit; Paul, Marilyn; Panda, Manoranjan; Jayaram, Shruthi; Kalidindi, Narasimharaju et al. (2021). Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology 31(10) . 10.1093/glycob/cwab072. [PDB: 7cxa] CMCF-ID Health
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] CMCF-ID Health
Lei, Ming; Tempel, Wolfram; Chen, Sizhuo; Liu, Ke; Min, Jinrong et al. (2019). Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1862(9) , 194409. 10.1016/j.bbagrm.2019.194409. CMCF-ID Health
Li, Franco K.K.; Gale, Robert T.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Brown, Eric D. et al. (2021). Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology 213(2) , 107733. 10.1016/j.jsb.2021.107733. [PDB: 6xh9, 6xhk, 6xhp, 6xhq, 6xhr, 6xhs, 6xht] CMCF-ID Health