Herrmann, Jonathan; Li, Po-Nan; Jabbarpour, Fatemeh; Chan, Anson C. K.; Rajkovic, Ivan et al. (2019). A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proceedings of the National Academy of Sciences of the United States of America 117(1) , 388-394. 10.1073/pnas.1909798116. [PDB: 6p5t] |
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Hersch, Steven J.; Watanabe, Nobuhiko; Stietz, Maria Silvina; Manera, Kevin; Kamal, Fatima et al. (2020). Envelope stress responses defend against type six secretion system attacks independently of immunity proteins. Nature Microbiology 5(5) . 10.1038/s41564-020-0672-6. [PDB: 6v98] |
CMCF-BM |
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Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] |
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Hill, Matthew D.; Quesnelle, Claude; Tokarski, John; Fang, Haiquan; Fanslau, Carolynn et al. (2021). Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype. Bioorganic and Medicinal Chemistry Letters 51, 128376. 10.1016/j.bmcl.2021.128376. [PDB: 7mce] |
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Hitchcock, Adam P.; Wang, Xiaoyue; Grandfield, Kathryn; Everett, James; Collingwood, Joanna F. et al. (2019). Correlative Spectromicroscopy and Tomography for Biomedical Applications Involving Electron, Ion, and Soft X-ray Microscopies. Microscopy Today 27(2) , 12-19. 10.1017/s1551929518001256. |
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Hobbs, Joanne K.; Pluvinage, Benjamin; Robb, Melissa; Smith, Steven P.; Boraston, Alisdair B. et al. (2019). Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. Journal of Biological Chemistry 294(34) , jbc.RA119.009368. 10.1074/jbc.ra119.009368. [PDB: 6or4] |
CMCF-BM, CMCF-ID |
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Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] |
CMCF-BM |
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Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] |
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Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] |
CMCF-ID |
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Huang, Ji; Nguyen, Vinh H.; Hamblin, Karleigh A.; Maytum, Robin; van der Giezen, Mark et al. (2019). ATP-specificity of succinyl-CoA synthetase fromBlastocystis hominis. Acta Crystallographica Section D: Structural Biology 75(7) , 647-659. 10.1107/s2059798319007976. [PDB: 6no1, 6no2, 6no3, 6no4] |
CMCF-ID |
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Hu, Carol H.; Neissel Valente, Meriah W.; Halpern, O. Scott; Jusuf, Sutjano; Khan, Javed A. et al. (2021). Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO). Bioorganic and Medicinal Chemistry Letters 42, 128010. 10.1016/j.bmcl.2021.128010. [PDB: 7lag, 7lan] |
CMCF-ID |
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Huhn, Annissa J.; Gardberg, Anna S.; Poy, Florence; Brucelle, Francois; Vivat, Valerie et al. (2020). Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. ChemMedChem 15(11) . 10.1002/cmdc.202000007. [PDB: 6v8n] |
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Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L. et al. (2020). Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Bioorganic and Medicinal Chemistry Letters 30(21) , 127495. 10.1016/j.bmcl.2020.127495. [PDB: 7jou] |
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Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] |
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Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2025). Structural and functional analysis of SAM-dependent N-methyltransferases involved in ovoselenol and ovothiol biosynthesis. Structure . 10.1016/j.str.2024.12.020. |
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