Publication Beamlines Strategic Pillar
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Depp, Charles T.; Goodman, Aaron J.; Blanchard, Peter.E.R.; Massimi, Scott E.; Reid, Joel W. et al. (2024). Potential for high-grade recovery of rare earth elements and cobalt from acid mine drainage via adsorption to precipitated manganese (IV) oxides. Chemosphere , 143144. 10.1016/j.chemosphere.2024.143144. BIOXAS-MAIN, CMCF-BM Environment
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] CMCF-BM, CMCF-ID Health
Dmitrienko, Anton; Britten, James F.; Spasyuk, Denis; Nikonov, Georgii I. (2019). Cover Feature: Adduct of NacNacAl with Benzophenone and Its Coupling Chemistry (Chem. Eur. J. 1/2020). Chemistry - A European Journal 26(1) , 2-2. 10.1002/chem.201904775. CMCF-BM Materials
Dong, Cheng; Nakagawa, Reiko; Oyama, Kyohei; Yamamoto, Yusuke; Zhang, Weilian et al. (2020). Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. eLife 9. 10.7554/elife.58675. [PDB: 6wat, 6wau] CMCF-BM, CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] CMCF-BM, CMCF-ID Health
Elikem, Essouassi; Laird, Brian D.; Hamilton, Jordan G.; Stewart, Katherine J.; Siciliano, Steven D. et al. (2019). Effects of chemical speciation on the bioaccessibility of zinc in spiked and smelter‐affected soils. Environmental Toxicology and Chemistry 38(2) . 10.1002/etc.4328. CMCF-BM, HXMA Environment
Enomoto, Masahiro; Nishikawa, Tadateru; Back, Sung-In; Ishiyama, Noboru; Zheng, Le et al. (2020). Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain. Journal of Molecular Biology 432(2) , 367-383. 10.1016/j.jmb.2019.10.003. [PDB: 6pw7] CMCF-BM Health
Fakih, Rayan; Goldstein, RobertH.; Kozlov, Guennadi; Gehring, Kalle (2023). Burst kinetics and CNNM binding are evolutionarily conserved properties of phosphatases of regenerating liver (PRL). Journal of Biological Chemistry , 103055. 10.1016/j.jbc.2023.103055. [PDB: 8ct8] CMCF-BM Health
Fakih, Rayan; Sauvé, Véronique; Gehring, Kalle (2022). Structure of the second phosphoubiquitin–binding site in parkin. Journal of Biological Chemistry 298(7) , 102114. 10.1016/j.jbc.2022.102114. [PDB: 7us1] CMCF-BM Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Fodje, Michel; Mundboth, Kiran; Labiuk, Shaunivan; Janzen, Kathryn; Gorin, James et al. (2020). Macromolecular crystallography beamlines at the Canadian Light Source: building on success. Acta Crystallographica Section D: Structural Biology 76(7) . 10.1107/s2059798320007603. CMCF-BM, CMCF-ID Health