Publication Beamlines Strategic Pillar
Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] CMCF-ID Health
Zhou, Qun; Jaworski, Julie; Zhou, Yanfeng; Valente, Delphine; Cotton, Joanne et al. (2020). Engineered Fc-glycosylation switch to eliminate antibody effector function. mAbs 12(1) , 1814583. 10.1080/19420862.2020.1814583. [PDB: 6x3i] CMCF-ID Health
Zhu, Yuao; Yurgelonis, Irina; Noell, Stephen; Yang, Qingyi; Guan, Shunjie et al. (2024). In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Science Advances 10(30) . 10.1126/sciadv.adl4013. [PDB: 9aum] CMCF-ID Health
Hettle, Andrew G.; Hobbs, Joanne K.; Pluvinage, Benjamin; Vickers, Chelsea; Abe, Kento T. et al. (2019). Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species. Communications Biology 2(1) . 10.1038/s42003-019-0721-y. [PDB: 6pnu, 6pop, 6prm, 6psm, 6pt4, 6ptk] CMCF-ID Environment
Hu, Zhenyu; Klupt, Kody; Zechel, David L.; Jia, Zongchao; Howe, Graeme W. et al. (2025). Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities using Sequence Similarity Networks. ChemBioChem . 10.1002/cbic.202500065. [PDB: 9eh6] CMCF-ID Environment
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal 109(3) . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Forrester, Taylor J. B.; Lin, Sicheng; Lowary, Todd L.; Kimber, Matthew S. (2025). WrtF from Rhizobium tropici CIAT 899 is a GT-A fold fucosyltransferase that binds its donor nonproductively. Proceedings of the National Academy of Sciences of the United States of America 122(44) . 10.1073/pnas.2512460122. [PDB: 9omh, 9omi] CMCF-BM, CMCF-ID Agriculture
Govind, Manitabhai; Allas, Mikel Jason; Huang, Bo-Shun; Lowary, Todd L.; Kimber, Matthew S. et al. (2026). The retaining kdo transferase that synthesizes Escherichia coli K13 capsule is deeply divergent from structurally homologous enzymes. Journal of Biological Chemistry 302(3) , 111162. 10.1016/j.jbc.2026.111162. [PDB: 9yfx] CMCF-ID Agriculture
Guo, Shuaiqi; Zahiri, Hossein; Stevens, Corey; Spaanderman, Daniel C.; Milroy, Lech-Gustav et al. (2021). Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain. Cell Reports 37(7) , 110002. 10.1016/j.celrep.2021.110002. [PDB: 6x5v, 6x5w] CMCF-ID Agriculture
Heide, Fabian; Stetefeld, Jörg (2022). A Structural Analysis of Proteinaceous Nanotube Cavities and Their Applications in Nanotechnology. Nanomaterials 12(22) , 4080. 10.3390/nano12224080. CMCF, CMCF-ID Agriculture
Xiao, Qin; Wang, Yu; Shang, Xinci; Chen, Yichang; Zhang, Ming et al. (2026). Structural basis for sequence-specific DNA recognition by a group IId WRKY transcription factor GhWRKY17 in cotton. Biochemical Journal 483(2) , 149-160. 10.1042/bcj20250191. [PDB: 9m0k] CMCF-ID Agriculture
Beh, Daniel W.; Cuellar De Lucio, Alejandro J.; del Rosal, Iker; Maron, Laurent; Spasyuk, Denis et al. (2023). Organotitanium Complexes Supported by a Dianionic Pentadentate Ligand. Organometallics 42(11) , 1149-1157. 10.1021/acs.organomet.2c00609. CMCF-BM Materials
Dmitrienko, Anton; Britten, James F.; Spasyuk, Denis; Nikonov, Georgii I. (2019). Cover Feature: Adduct of NacNacAl with Benzophenone and Its Coupling Chemistry (Chem. Eur. J. 1/2020). Chemistry - A European Journal 26(1) , 2-2. 10.1002/chem.201904775. CMCF-BM Materials
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Materials
Hogan, David T.; Gelfand, Benjamin S.; Spasyuk, Denis M.; Sutherland, Todd C. (2020). Subtle substitution controls the rainbow chromatic behaviour of multi-stimuli responsive core-expanded pyrenes. Materials Chemistry Frontiers 4(1) , 268-276. 10.1039/c9qm00710e. CMCF-BM Materials