Publication Beamlines Strategic Pillar
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] CMCF-ID Health
Keylor, Mitchell H.; Gulati, Anmol; Kattar, Solomon D.; Johnson, Rebecca E.; Chau, Ryan W. et al. (2021). Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. Journal of Medicinal Chemistry 65(1) , 838-856. 10.1021/acs.jmedchem.1c01968. [PDB: 7suh] CMCF-ID Health
Khan, Nimra; Pelletier, Dylan; Veyron, Simon; Croteau, Nathalie; Ichikawa, Muneyoshi et al. (2019). Crystal structure of human PACRG in complex with MEIG1. FEMS Microbiology Ecology . 10.1101/783373. [PDB: 6ndu, 6ucc] CMCF-ID Health
Khondker, Adree; Alsop, Richard J.; Himbert, Sebastian; Tang, Jennifer; Shi, An-Chang et al. (2018). Membrane-Modulating Drugs can Affect the Size of Amyloid-β25–35 Aggregates in Anionic Membranes. Scientific Reports 8(1) , 12367:1-16. 10.1038/s41598-018-30431-8. SM Health
Kim, Hyeong Jin; Black, Mazzen; Edwards, Ross A.; Peillard-Fiorente, Flora; Panigrahi, Rashmi et al. (2022). Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones. Nature Communications 13(1) . 10.1038/s41467-022-34875-5. [PDB: 7rgt] CMCF-ID Health
King, Moeko Toride; Huh, Ian; Shenai, Akhilesh; Brooks, Teresa M.; Brooks, Cory L. et al. (2018). Structural basis of VHH-mediated neutralization of the food-borne pathogen Listeria monocytogenes. Journal of Biological Chemistry 293(35) , 13626-13635. 10.1074/jbc.ra118.003888. [PDB: 6dba, 6dbd, 6dbe, 6dbf, 6dbg] CMCF-ID Health
Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph et al. (2025). Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis. Journal of Medicinal Chemistry 68(8) , 8713-8728. 10.1021/acs.jmedchem.5c00390. [PDB: 9n9l] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health
Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. CMCF Health
Kozlov, Guennadi; Mattijssen, Sandy; Jiang, Jianning; Nyandwi, Samuel; Sprules, Tara et al. (2022). Structural basis of 3′-end poly(A) RNA recognition by LARP1. Nucleic Acids Research 50(16) , 9534-9547. 10.1093/nar/gkac696. [PDB: 7soo, 7sop] CMCF-ID Health
Krishnan, Shreya S; Shen, Yao; O’Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W et al. (2025). Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. Nucleic Acids Research 53(11) . 10.1093/nar/gkaf472. CMCF-BM Health
Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] CMCF-ID Health
Kuduk, Scott D.; Stoops, Bart; Alexander, Richard; Lam, Angela M.; Espiritu, Christine et al. (2021). Identification of a new class of HBV capsid assembly modulator. Bioorganic and Medicinal Chemistry Letters 39, 127848. 10.1016/j.bmcl.2021.127848. [PDB: 7k5m] CMCF-ID Health
Kumar, Amit; Paul, Marilyn; Panda, Manoranjan; Jayaram, Shruthi; Kalidindi, Narasimharaju et al. (2021). Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology 31(10) . 10.1093/glycob/cwab072. [PDB: 7cxa] CMCF-ID Health
Kundu, Prasun; Semesi, Anthony; Jore, Matthijs M.; Morin, Merribeth J.; Price, Virginia L. et al. (2018). Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nature Communications 9(1) . 10.1038/s41467-018-06742-9. [PDB: 6e62, 6e63, 6e64, 6e65] CMCF-ID Health