Publication Beamlines Strategic Pillar
Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] CMCF-ID Health
Harikrishnan, Lalgudi S.; Gill, Patrice; Kamau, Muthoni G.; Qin, Lan-Ying; Ruan, Zheming et al. (2020). Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists. Bioorganic and Medicinal Chemistry Letters 30(12) , 127204. 10.1016/j.bmcl.2020.127204. [PDB: 6xae] CMCF-ID Health
Hamaguchi, Hisao; Amano, Yasushi; Moritomo, Ayako; Shirakami, Shohei; Nakajima, Yutaka et al. (2018). Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor. Bioorganic and Medicinal Chemistry 26(18) , 4971-4983. 10.1016/j.bmc.2018.08.005. [PDB: 6aak] CMCF-ID Health
Hallett, Robin M.; Bonfill-Teixidor, Ester; Iurlaro, Raffaella; Arias, Alexandra; Raman, Swetha et al. (2022). Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment. Clinical Cancer Research 29(4) , 791-804. 10.1158/1078-0432.ccr-21-1888. CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L.; MacKenzie, C. Roger; Caveney, Nathanael et al. (2018). Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry 58(6) , 714-726. 10.1021/acs.biochem.8b00318. [PDB: 6c5h, 6c5i, 6c5j, 6c5k] CMCF-ID Health
Gytz, Heidi; Liang, Jason; Liang, Yingke; Gorelik, Alexei; Illes, Katalin et al. (2019). The structure of mammalian β‐mannosidase provides insight into β‐mannosidosis and nystagmus. FEBS Journal 286(7) . 10.1111/febs.14731. [PDB: 6ddt, 6ddu] CMCF-ID Health
Guo, Shuaiqi; Vance, Tyler D. R.; Zahiri, Hossein; Eves, Robert; Stevens, Corey et al. (2021). Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation. mBio 12(2) . 10.1128/mbio.00130-21. [PDB: 6x7j, 6x7t, 6x7y, 6x7z, 6x8a, 6x8d, 6x8y, 6x95, 6x9m, 6x9p, 6xa5, 6xaq] CMCF-ID Health
Guo, Shuaiqi; Langelaan, David N.; Phippen, Sean W.; Smith, Steven P.; Voets, Ilja K. et al. (2018). Conserved structural features anchor biofilm‐associated RTX –adhesins to the outer membrane of bacteria. FEBS Journal 285(10) , 1812-1826. 10.1111/febs.14441. CMCF-ID Health
Gui, Wenjun; Hang, Yumo; Cheng, Wang; Gao, Minqi; Wu, Jiaquan et al. (2023). Structural basis of CDK3 activation by cyclin E1 and inhibition by dinaciclib. Biochemical and Biophysical Research Communications 662, 126-134. 10.1016/j.bbrc.2023.04.026. CMCF-BM, CMCF-ID Health
Gruninger, Robert J.; Kevorkova, Maya; Low, Kristin E.; Jones, Darryl R.; Worrall, Liam et al. (2024). Structural, Biochemical, and Phylogenetic Analysis of Bacterial and Fungal Carbohydrate Esterase Family 15 Glucuronoyl Esterases in the Rumen. Protein Journal 43(4) , 910-922. 10.1007/s10930-024-10221-0. [PDB: 8tru, 8trx, 8tse] CMCF-ID Health
Grant, Benjamin M. M.; Enomoto, Masahiro; Back, Sung-In; Lee, Ki-Young; Gebregiworgis, Teklab et al. (2020). Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety. Science Signaling 13(625) , eaaz0344. 10.1126/scisignal.aaz0344. [PDB: 6os4] CMCF-ID Health
Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2018). Structural basis for nucleotide recognition by the ectoenzyme CD 203c. FEBS Journal 285(13) . 10.1111/febs.14489. [PDB: 6c01, 6c02] CMCF-ID Health
Gorelik, Alexei; Labriola, Jonathan M.; Illes, Katalin; Nagar, Bhushan (2020). Crystal structure of the nucleotide‐metabolizing enzyme NTPDase4. Protein Science 29(10) . 10.1002/pro.3926. [PDB: 6wg5] CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2018). Crystal structure of the mammalian lipopolysaccharide detoxifier. Proceedings of the National Academy of Sciences of the United States of America 115(5) , E896-E905. 10.1073/pnas.1719834115. [PDB: 5w78, 5w7a, 5w7b, 5w7c, 5w7d, 5w7e, 5w7f] CMCF-ID Health
Gorelik, Alexei; Gebai, Ahmad; Illes, Katalin; Piomelli, Daniele; Nagar, Bhushan et al. (2018). Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America 115(43) , E10032-E10040. 10.1073/pnas.1811759115. [PDB: 6dxw, 6dxx, 6dxy, 6dxz, 6dy0, 6dy1, 6dy2, 6dy3] CMCF-BM, CMCF-ID Health