Publication Beamlines Strategic Pillar
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Whittington, Douglas A.; Jahic, Haris; Ali, Janid A. et al. (2024). Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers. Journal of Medicinal Chemistry 67(8) , 6064-6080. 10.1021/acs.jmedchem.4c00133. [PDB: 8veu] CMCF-ID Health
Courchesne, Brittaney; Schindler, Michael; Mykytczuk, Nadia C. S. (2021). Relationships Between the Microbial Composition and the Geochemistry and Mineralogy of the Cobalt-Bearing Legacy Mine Tailings in Northeastern Ontario. Frontiers in Microbiology 12. 10.3389/fmicb.2021.660190. VESPERS Environment
Coutant, Maxime; Lepot, Kevin; Fadel, Alexandre; Addad, Ahmed; Richard, Elodie et al. (2022). Distinguishing cellular from abiotic spheroidal microstructures in the ca. 3.4 Ga Strelley Pool Formation. Geobiology 20(5) , 599-622. 10.1111/gbi.12506. SM Environment
Cranston, Rosemary R.; Vebber, Mário C.; Berbigier, Jônatas Faleiro; Rice, Nicole A.; Tonnelé, Claire et al. (2020). Thin-Film Engineering of Solution-Processable n-Type Silicon Phthalocyanines for Organic Thin-Film Transistors. ACS Applied Materials and Interfaces 13(1) , 1008-1020. 10.1021/acsami.0c17657. HXMA Materials
Cranston, Rosemary R.; Vebber, Mário C.; Faleiro Berbigier, Jônatas; Brusso, Jaclyn; Kelly, Timothy L. et al. (2022). High Performance Solution Processed n‐Type OTFTs through Surface Engineered F–F Interactions Using Asymmetric Silicon Phthalocyanines. Advanced Electronic Materials , 2200696. 10.1002/aelm.202200696. BXDS-WLE Materials
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Critton, D.A. (2024). Crystal structure of monkey TLR7 ectodomain with compound 14. Protein Data Bank: 8s9h. CMCF-ID Health
Cron, Brandi; Macalady, Jennifer L.; Cosmidis, Julie (2021). Organic Stabilization of Extracellular Elemental Sulfur in a Sulfurovum-Rich Biofilm: A New Role for Extracellular Polymeric Substances?. Frontiers in Microbiology 12. 10.3389/fmicb.2021.720101. SM Environment
Cron, Brandi; Macalady, Jennifer L.; Cosmidis, Julie (2021). Organic stabilization of extracellular elemental sulfur in a Sulfurovum-rich biofilm: a new role for EPS?. Patent Number: 10.1101/2021.06.03.446708. Environment
Cron, Brandi R.; Sheik, Cody S.; Kafantaris, Fotios-Christos A.; Druschel, Gregory K.; Seewald, Jeffrey S. et al. (2019). Dynamic Biogeochemistry of the Particulate Sulfur Pool in a Buoyant Deep-Sea Hydrothermal Plume. ACS Earth and Space Chemistry 4(2) , 168-182. 10.1021/acsearthspacechem.9b00214. SXRMB
Crowe; Adam Michael (2018). The catabolism of the last two rings of cholesterol by Mycobacterium tuberculosis. Supervisor: Eltis, Lindsay D.. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/64634. CMCF-BM
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in Mycobacterium tuberculosis , is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] CMCF-BM Health
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Mycobacterium tuberculosis IpdAB. Protein Data Bank: 6con. CMCF-BM Health