| Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N. G. (2018). Structural characterization of
POM
6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS Journal 285(9) , 1701-1714. 10.1111/febs.14438. [PDB: 6aq7] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Bamford, Natalie C.; Le Mauff, François; Subramanian, Adithya S.; Yip, Patrick; Millán, Claudia et al. (2019). Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1,4-galactosaminidase that disrupts microbial biofilms. Journal of Biological Chemistry 294(37) , 13833-13849. 10.1074/jbc.ra119.009910. [PDB: 6oj1] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Bai, Bing; Belovodskiy, Alexandr; Hena, Mostofa; Kandadai, Appan Srinivas; Joyce, Michael A. et al. (2021). Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability. Journal of Medicinal Chemistry 65(4) . 10.1021/acs.jmedchem.1c00616. |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Almawi, Ahmad W; Scotland, Michelle K; Randall, Justin R; Liu, Linda; Martin, Heather K et al. (2019). Binding of the regulatory domain of MutL to the sliding β-clamp is species specific. Nucleic Acids Research 47(9) . 10.1093/nar/gkz115. [PDB: 6e8d, 6e8e] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Ali, Mohamed G.; Wahba, Haytham M.; Igelmann, Sebastian; Cyr, Normand; Ferbeyre, Gerardo et al. (2024). Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy . 10.1080/15548627.2024.2353443. [PDB: 8t33, 8t4t] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Alexander, J. Andrew N.; Chatterjee, Som S.; Hamilton, Stephanie M.; Eltis, Lindsay D.; Chambers, Henry F. et al. (2018). Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. Journal of Biological Chemistry 293(51) , 19854-19865. 10.1074/jbc.ra118.004952. [PDB: 5tw4, 5tw8, 5tx9, 5txi, 5ty2, 5ty7, 6c39, 6c3k] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Aggett, Rebecca; Mallette, Evan; Gilbert, Stephanie E.; Vachon, Melody A.; Schroeter, Kurt L. et al. (2019). The steroid side-chain–cleaving aldolase Ltp2–ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site. Journal of Biological Chemistry 294(31) , jbc.RA119.008889. 10.1074/jbc.ra119.008889. [PDB: 6ok1] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Abraham, Nadine; Schroeter, Kurt L.; Zhu, Yan; Chan, Jonathan; Evans, Natasha et al. (2022). Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol. Scientific Reports 12(1) . 10.1038/s41598-022-19040-8. [PDB: 7utf] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| van Vliet, Vera J. E.; Huynh, Nhan; Palà, Judith; Patel, Ankoor; Singer, Alex et al. (2022). Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathogens 18(12) , e1011065. 10.1371/journal.ppat.1011065. |
CMCF |
Peer-Reviewed Article |
Health |
| Sankhe, Safiétou; Fofana, Fatoumata G.; Heiba, Walid; Ogunyemi, Oludare M.; Masisi, Kabo et al. (2025). BioStruct-Africa’s capacity building workshops as a model for advancing the emerging community of structural biologists in Africa. Communications Chemistry 8(1) . 10.1038/s42004-025-01519-w. |
CMCF |
Peer-Reviewed Article |
Health |
| Patel, Ankoor; McBride, Jessica A.M.; Mark, Brian L. (2021). The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. Journal of Biological Chemistry 297(2) , 100957. 10.1016/j.jbc.2021.100957. |
CMCF |
Peer-Reviewed Article |
Health |
| Mundboth, Kiran (2025). Canadian Light Source – 20 Years of Discovery. Canadian Journal of Chemistry . 10.1139/cjc-2024-0278. |
BMIT, BXDS, CMCF, FAR-IR, HXMA, MID-IR, SM |
Peer-Reviewed Article |
Health |
| Meier, Markus; Gupta, Monika; Akgül, Serife; McDougall, Matthew; Imhof, Thomas et al. (2023). The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nature Communications 14(1) . 10.1038/s41467-023-36692-w. |
CMCF |
Peer-Reviewed Article |
Health |
| Kozlov, Guennadi; Funato, Yosuke; Chen, Yu Seby; Zhang, Zhidian; Illes, Katalin et al. (2020). PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth. Journal of Biological Chemistry 295(33) , 11682-11692. 10.1074/jbc.ra120.014464. |
CMCF |
Peer-Reviewed Article |
Health |