Publication Beamlines Strategic Pillar
Ishiyama, Noboru; Sarpal, Ritu; Wood, Megan N.; Barrick, Samantha K.; Nishikawa, Tadateru et al. (2018). Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions. Nature Communications 9(1) . 10.1038/s41467-018-07481-7. [PDB: 6duw, 6duy, 6dv1] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2025). Structural and functional analysis of SAM-dependent N-methyltransferases involved in ovoselenol and ovothiol biosynthesis. Structure . 10.1016/j.str.2024.12.020. CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health
Imkeller, Katharina; Scally, Stephen W.; Bosch, Alexandre; Martí, Gemma Pidelaserra; Costa, Giulia et al. (2018). Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science 360(6395) , 1358-1362. 10.1126/science.aar5304. [PDB: 6d01, 6d11] CMCF-ID Health
Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] CMCF-ID Health
Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L. et al. (2020). Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Bioorganic and Medicinal Chemistry Letters 30(21) , 127495. 10.1016/j.bmcl.2020.127495. [PDB: 7jou] CMCF-ID Health
Huhn, Annissa J.; Gardberg, Anna S.; Poy, Florence; Brucelle, Francois; Vivat, Valerie et al. (2020). Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. ChemMedChem 15(11) . 10.1002/cmdc.202000007. [PDB: 6v8n] CMCF-ID Health
Huguenin-Dezot, Nicolas; Alonzo, Diego A.; Heberlig, Graham W.; Mahesh, Mohan; Nguyen, Duy P. et al. (2018). Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature 565(7737) , 112-117. 10.1038/s41586-018-0781-z. [PDB: 6ecb, 6ecc, 6ece, 6ecf] CMCF-ID Health
Hu, Carol H.; Neissel Valente, Meriah W.; Halpern, O. Scott; Jusuf, Sutjano; Khan, Javed A. et al. (2021). Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO). Bioorganic and Medicinal Chemistry Letters 42, 128010. 10.1016/j.bmcl.2021.128010. [PDB: 7lag, 7lan] CMCF-ID Health
Huang, Joyce; Tian, Jing; Chung, Tzu Chun; Denton, Sam; Teng, Youchao et al. (2026). Biocompatible, Ion-Conductive Hydrogel-Filled Nerve Conduit for Peripheral Nerve Regeneration. ACS Applied Materials and Interfaces . 10.1021/acsami.5c19623. BXDS-WLE Health
Huang, Ji; Nguyen, Vinh H.; Hamblin, Karleigh A.; Maytum, Robin; van der Giezen, Mark et al. (2019). ATP-specificity of succinyl-CoA synthetase fromBlastocystis hominis. Acta Crystallographica Section D: Structural Biology 75(7) , 647-659. 10.1107/s2059798319007976. [PDB: 6no1, 6no2, 6no3, 6no4] CMCF-ID Health
Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] CMCF-ID Health
Huang, Christine S.; Oberbeck, Nina; Hsiao, Yi-Chun; Liu, Peter; Johnson, Adam R. et al. (2018). Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure 26(5) , 767-777.e5. 10.1016/j.str.2018.04.002. [PDB: 5wni] CMCF-ID Health
Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] CMCF-ID Health
Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] CMCF-BM Health