Publication Beamlines Strategic Pillar
Li, Franco K.K.; Gale, Robert T.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Brown, Eric D. et al. (2021). Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology 213(2) , 107733. 10.1016/j.jsb.2021.107733. [PDB: 6xh9, 6xhk, 6xhp, 6xhq, 6xhr, 6xhs, 6xht] CMCF-ID Health
Li, Franco K.K.; Rosell, Federico I.; Gale, Robert T.; Simorre, Jean-Pierre; Brown, Eric D. et al. (2020). Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. Journal of Biological Chemistry 295(9) , 2629-2639. 10.1074/jbc.ra119.011469. [PDB: 6uex, 6uf3, 6uf5, 6uf6] CMCF-ID Health
Li, Franco K. K.; Worrall, Liam J.; Gale, Robert T.; Brown, Eric D.; Strynadka, Natalie C. J. et al. (2024). Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance. Science Advances 10(9) . 10.1126/sciadv.adj3864. [PDB: 8v33] CMCF-ID Health
Li, Jia; Jia, Yunhua; Lin, Aiyang; Hanna, Michelle; Chelico, Linda et al. (2019). Structure of Ddi2, a highly inducible detoxifying metalloenzyme from Saccharomyces cerevisiae. Journal of Biological Chemistry 294(27) , 10674-10685. 10.1074/jbc.ra118.006394. [PDB: 6dk9, 6dka, 6dkc, 6dkd] CMCF-BM, CMCF-ID Health
Li, Kunhua; Tokareva, Olena S.; Thomson, Ty M.; Wahl, Sebastian C. T.; Travaline, Tara L. et al. (2022). De novo mapping of α-helix recognition sites on protein surfaces using unbiased libraries. Proceedings of the National Academy of Sciences of the United States of America 119(52) . 10.1073/pnas.2210435119. [PDB: 7uwi] CMCF-ID Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. [PDB: 6mne] CMCF-BM, CMCF-ID Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Liu, Jian; Yu, Younong; Kelly, Joseph; Sha, Deyou; Alhassan, Abdul-Basit et al. (2020). Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group. ACS Medicinal Chemistry Letters 11(12) , 2476-2483. 10.1021/acsmedchemlett.0c00462. [PDB: 7kbg] CMCF-ID Health
Liu, Ke; Xu, Chao; Lei, Ming; Yang, Ally; Loppnau, Peter et al. (2018). Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. Journal of Biological Chemistry 293(19) , 7344-7354. 10.1074/jbc.ra118.001785. [PDB: 6c1t, 6c1u, 6c1v] CMCF-ID Health
Liu, Weifeng; Maben, Zachary; Wang, Carole; Lindquist, Kevin C.; Li, Manqing et al. (2021). Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. Journal of Biological Chemistry 297(4) , 101102. 10.1016/j.jbc.2021.101102. [PDB: 7kx0] CMCF-ID Health
Liu, Yanli; Qin, Su; Chen, Tsai-Yu; Lei, Ming; Dhar, Shilpa S. et al. (2019). Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nature Communications 10(1) . 10.1038/s41467-018-07906-3. [PDB: 6mlc] CMCF-ID Health
Lizak, Christian; Worrall, Liam J.; Baumann, Lars; Pfleiderer, Moritz M.; Volkers, Gesa et al. (2017). X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Scientific Reports 7(1) . 10.1038/s41598-017-05627-z. [PDB: 5wc6, 5wcn, 5wd7] CMCF-BM, CMCF-ID Health
Li, Zhijie; Fischer, Michael; Satkunarajah, Malathy; Zhou, Dongxia; Withers, Stephen G. et al. (2017). Structural basis of Notch O-glucosylation and O–xylosylation by mammalian protein–O-glucosyltransferase 1 (POGLUT1). Nature Communications 8(1) . 10.1038/s41467-017-00255-7. [PDB: 5l0r, 5l0s, 5l0t] CMCF-ID Health
Li, Zhijie; Han, Kristina; Pak, John E; Satkunarajah, Malathy; Zhou, Dongxia et al. (2017). Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1. Nature Chemical Biology 13(7) . 10.1038/nchembio.2381. [PDB: 5kxh, 5kxq, 5ky0, 5ky2, 5ky3, 5ky4, 5ky5, 5ky7, 5ky8, 5ky9] CMCF-ID Health
Li, Zhijie; Tomlinson, Aidan CA; Wong, Alan HM; Zhou, Dongxia; Desforges, Marc et al. (2019). The human coronavirus HCoV-229E S-protein structure and receptor binding. eLife 8. 10.7554/elife.51230. [PDB: 6u7e, 6u7f] CMCF-ID Health