Publication Beamlines Strategic Pillar
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Beenstock, Jonah; Ona, Samara Mishelle; Porat, Jennifer; Orlicky, Stephen; Wan, Leo C. K. et al. (2020). A substrate binding model for the KEOPS tRNA modifying complex. Nature Communications 11(1) . 10.1038/s41467-020-19990-5. [PDB: 7kju] CMCF-ID Health
Beshore, Douglas C.; Adam, Gregory C.; Barnard, Richard J. O.; Burlein, Christine; Gallicchio, Steven N. et al. (2021). Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction. ACS Medicinal Chemistry Letters 12(4) , 540-547. 10.1021/acsmedchemlett.1c00074. [PDB: 7ltg] CMCF-ID Health
Beyrakhova, Ksenia; Li, Lei; Xu, Caishuang; Gagarinova, Alla; Cygler, Miroslaw et al. (2018). Legionella pneumophila effector Lem4 is a membrane-associated protein tyrosine phosphatase. Journal of Biological Chemistry 293(34) , 13044-13058. 10.1074/jbc.ra118.003845. [PDB: 6cdw, 6cgj] CMCF-ID Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Bissegger, Lukas; Constantin, Theodora A.; Keles, Erhan; Raguž, Luka; Barlow-Busch, Isobel et al. (2024). Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling. Chemical Science . 10.1039/d4sc05459h. [PDB: 8twy] CMCF-ID Health
Blackler, Ryan J.; López-Guzmán, Arturo; Hager, Fiona F.; Janesch, Bettina; Martinz, Gudrun et al. (2018). Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Nature Communications 9(1) . 10.1038/s41467-018-05471-3. [PDB: 6cwc, 6cwh, 6cwi, 6cwl, 6cwm, 6cwn, 6cwr] CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. [PDB: 6bxr, 6bxs] CMCF-BM, CMCF-ID Health
Boddington, Kelly F.; Soubeyrand, Eric; Van Gelder, Kristen; Casaretto, José A.; Perrin, Colby et al. (2021). Bibenzyl synthesis in Cannabis sativa L.. Plant Journal 109(3) . 10.1111/tpj.15588. [PDB: 7sgy] CMCF-ID Agriculture
Bonday, Zahid Q.; Cortez, Guillermo S.; Grogan, Michael J.; Antonysamy, Stephen; Weichert, Ken et al. (2018). LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Medicinal Chemistry Letters 9(7) , 612-617. 10.1021/acsmedchemlett.8b00014. [PDB: 6ckc] CMCF-ID Health
Boniecki, Michal T.; Freibert, Sven A.; Mühlenhoff, Ulrich; Lill, Roland; Cygler, Miroslaw et al. (2017). Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nature Communications 8(1) . 10.1038/s41467-017-01497-1. [PDB: 5wgb, 5wkp, 5wlw] CMCF-ID Health
Borsari, Chiara; Keles, Erhan; McPhail, Jacob A.; Schaefer, Alexander; Sriramaratnam, Rohitha et al. (2022). Covalent Proximity Scanning of a Distal Cysteine to Target PI3Kα. Journal of the American Chemical Society 144(14) . 10.1021/jacs.1c13568. [PDB: 7r9v, 7r9y] CMCF-ID Health
Bryan, Marian C.; Drobnick, Joy; Gobbi, Alberto; Kolesnikov, Aleksandr; Chen, Yongsheng et al. (2019). Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Journal of Medicinal Chemistry 62(13) . 10.1021/acs.jmedchem.9b00439. [PDB: 6o9d] CMCF-ID Health
Bullen, Nathan P.; Sychantha, David; Thang, Stephanie S.; Culviner, Peter H.; Rudzite, Marta et al. (2022). An ADP-ribosyltransferase toxin kills bacterial cells by modifying structured non-coding RNAs. Molecular Cell 82(18) , 3484-3498.e11. 10.1016/j.molcel.2022.08.015. CMCF-ID Health
Caldwell, Shane J.; Berghuis, Albert M. (2018). Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2″)-Ia. Antimicrobial Agents and Chemotherapy 62(7) , e00202-18. 10.1128/aac.00202-18. [PDB: 6c5u, 6cav, 6cey, 6cgd, 6cgg, 6ch4] CMCF-ID Health