Publication Beamlines Strategic Pillar
Ramasubramanian, Anusuya; Tennyson, Rachel; Magnay, Maureen; Kathuria, Sagar; Travaline, Tara et al. (2020). Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies 9(4) , 62. 10.3390/antib9040062. [PDB: 7jkb] CMCF-ID Health
Rasool, Shafqat; Veyron, Simon; Soya, Naoto; Eldeeb, Mohamed A.; Lukacs, Gergely L. et al. (2022). Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Molecular Cell 82(1) , 44-59. 10.1016/j.molcel.2021.11.012. CMCF-ID Health
Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] CMCF-ID Health
Reimer, Janice M.; Eivaskhani, Maximilian; Harb, Ingrid; Guarné, Alba; Weigt, Martin et al. (2019). Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science 366(6466) , eaaw4388. 10.1126/science.aaw4388. [PDB: 6mfw, 6mfx, 6mfy, 6mfz] CMCF-ID Health
Reimer, Janice M.; Harb, Ingrid; Ovchinnikova, Olga G.; Jiang, Jessie; Whitfield, Chris et al. (2018). Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain. ACS Chemical Biology 13(11) , 3161-3172. 10.1021/acschembio.8b00739. [PDB: 6ci2, 6ci5] CMCF-ID Health
Rescourio, Gwenaella; Gonzalez, Ana Z.; Jabri, Salman; Belmontes, Brian; Moody, Gordon et al. (2019). Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. Journal of Medicinal Chemistry 62(22) , 10258-10271. 10.1021/acs.jmedchem.9b01310. [PDB: 6ud2, 6udi] CMCF-ID Health
Rice, Kyle; Batul, Kissa; Whiteside, Jacqueline; Kelso, Jayne; Papinski, Monica et al. (2019). The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis. Nature Communications 10(1) . 10.1038/s41467-019-11627-6. CMCF-ID Health
Richardson-Sanchez, Tomas; Chan, Anson C. K.; Sabatino, Brendil; Lin, Helen; Gaynor, Erin C. et al. (2023). Dissecting components of theCampylobacter jejuni fetMP-fetABCDEFgene cluster in iron scavenging. Tribology Letters . 10.1101/2023.07.05.547857. [PDB: 8t4c] CMCF-ID Health
Riggs, Jennifer R.; Elsner, Jan; Cashion, Dan; Robinson, Dale; Tehrani, Lida et al. (2019). Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy. Journal of Medicinal Chemistry 62(9) , 4401-4410. 10.1021/acs.jmedchem.8b01869. [PDB: 6n6o] CMCF-ID Health
Riggs, Jennifer R.; Nagy, Mark; Elsner, Jan; Erdman, Paul; Cashion, Dan et al. (2017). The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen. Journal of Medicinal Chemistry 60(21) , 8989-9002. 10.1021/acs.jmedchem.7b01223. [PDB: 6b4w] CMCF-ID Health
Rutbeek, Nicole R.; Rezasoltani, Hanieh; Patel, Trushar R.; Khajehpour, Mazdak; Prehna, Gerd et al. (2021). Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox. Journal of Biological Chemistry 297(3) , 100992. 10.1016/j.jbc.2021.100992. CMCF-ID Health
Ryan, Patrick; Forrester, Taylor J.B.; Wroblewski, Charles; Kenney, Tristan M.G.; Kitova, Elena N. et al. (2019). The small RbcS-like domains of the β-carboxysome structural protein CcmM bind RubisCO at a site distinct from that binding the RbcS subunit. Journal of Biological Chemistry 294(8) , 2593-2603. 10.1074/jbc.ra118.006330. [PDB: 6mr1] CMCF-ID Health
Sahtout, Naheda; Kuttiyatveetil, Jijin R.A.; Sanders, David A.R. (2019). Structure and function of the putative thioredoxin 1 from the thermophilic eubacterium Thermosipho africanus strain TCF52B. Biochimica et Biophysica Acta - Proteins and Proteomics 1867(4) , 426-433. 10.1016/j.bbapap.2019.01.011. [PDB: 6mos] CMCF-ID Health
Sakurada, Isao; Endo, Toshiya; Hikita, Katsuyoshi; Hirabayashi, Tomokazu; Hosaka, Yoshitaka et al. (2017). Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors. Bioorganic and Medicinal Chemistry Letters 27(11) , 2622-2628. 10.1016/j.bmcl.2017.03.002. [PDB: 5tnt] CMCF-ID Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health