Publication Beamlines Strategic Pillar
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia et al. (2018). Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORĪ³/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Bioorganic and Medicinal Chemistry Letters 28(2) , 85-93. 10.1016/j.bmcl.2017.12.006. [PDB: 6bns] CMCF-ID Health
Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] CMCF-ID Health
Golkar, Tolou; Bassenden, Angelia V.; Maiti, Krishnagopal; Arya, Dev P.; Schmeing, T. Martin et al. (2021). Structural basis for plazomicin antibiotic action and resistance. Communications Biology 4(1) . 10.1038/s42003-021-02261-4. [PDB: 6vou, 7lh5] CMCF-ID Health