Publication Beamlines Strategic Pillar
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Sharon, Itai; McKay, Geoffrey A.; Nguyen, Dao; Schmeing, T. Martin (2023). Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proceedings of the National Academy of Sciences of the United States of America 120(8) . 10.1073/pnas.2216547120. CMCF-BM Health
Sharon, Itai; Schmeing, T. Martin (2023). Bioinformatics of cyanophycin metabolism genes and characterization of promiscuous isoaspartyl dipeptidases that catalyze the final step of cyanophycin degradation. Scientific Reports 13(1) . 10.1038/s41598-023-34587-w. CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Shen, Y.; Guarne, A. (2022). Crystal structure of TnsC(1-503)A225V. Protein Data Bank: 7mbw. CMCF-BM Health
Shurtleff, Valerie W.; Layton, Mark E.; Parish, Craig A.; Perkins, James J.; Schreier, John D. et al. (2024). Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c02248. [PDB: 8ute] CMCF-BM Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100016. Protein Data Bank: 9cux. CMCF-BM Health
Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100013. Protein Data Bank: 9cuw. CMCF-BM Health
Smirnova, Ekaterina (2017). Structure-Function Studies of Scaffolding Proteins Involved in the Formation of Neuronal Connections : AIDA1 and CASKIN2. Supervisor: Donaldson, Logan. ON, Canada: York University. http://hdl.handle.net/10315/33546. CMCF-BM Health
Smirnova, Ekaterina; Kwan, Jamie J.; Siu, Ryan; Gao, Xin; Zoidl, Georg et al. (2016). A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Communication and Signaling 14(1) , 17. 10.1186/s12964-016-0140-3. [PDB: 5l1m] CMCF-BM Health
Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] CMCF-BM, CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. [PDB: 5tzi, 5tzj, 5u02] CMCF-BM, CMCF-ID Health
Sokaribo, Akosiererem; Novakovski, Brian A.A.; Cotelesage, Julien; White, Aaron P.; Sanders, David et al. (2020). Kinetic and structural analysis of Escherichia coli phosphoenolpyruvate carboxykinase mutants. Biochimica et Biophysica Acta - General Subjects 1864(4) , 129517. 10.1016/j.bbagen.2020.129517. [PDB: 6v2l, 6v2m, 6v2n] CMCF-BM, CMCF-ID Health
Stevenson, James; Ngo, Maria; Brandt, Alicia; Weadge, Joel T.; Suits, Michael D. L. et al. (2021). Analysis of Two SusE-Like Enzymes From Bacteroides thetaiotaomicron Reveals a Potential Degradative Capacity for This Protein Family. Frontiers in Microbiology 12. 10.3389/fmicb.2021.645765. [PDB: 7m1a, 7m1b] CMCF-BM Health
Stille, Julia K.; Tjutrins, Jevgenijs; Wang, Guanyu; Venegas, Felipe A.; Hennecker, Christopher et al. (2022). Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors. European Journal of Medicinal Chemistry 229, 114046. 10.1016/j.ejmech.2021.114046. [PDB: 7mlf] CMCF-BM Health