| Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 and egg Juno complex. Protein Data Bank: 5f4e. |
CMCF-ID |
PDB Deposition |
Health |
| Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 residues 22-268. Protein Data Bank: 5f4v. |
CMCF-ID |
PDB Deposition |
Health |
| Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tang, Y.; Poy, F.; Bellon, S.F. (2016). TAF1(2) bound to a pyrrolopyridone compound. Protein Data Bank: 5i29. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Crawford, Terry D.; Tsui, Vickie; Flynn, E. Megan; Wang, Shumei; Taylor, Alexander M. et al. (2016). Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. Journal of Medicinal Chemistry 59(11) , 5391-5402. 10.1021/acs.jmedchem.6b00264. [PDB: 5i29] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib. Protein Data Bank: 5aac. |
CMCF-ID |
PDB Deposition |
Health |
| Scapin, G. (2016). Human DPP4 in complex with a novel tricyclic hetero-cycle inhibitor. Protein Data Bank: 5i7u. |
CMCF-ID |
PDB Deposition |
Health |
| Wu, Wen-Lian; Hao, Jinsong; Domalski, Martin; Burnett, Duane A.; Pissarnitski, Dmitri et al. (2016). Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. ACS Medicinal Chemistry Letters 7(5) , 498-501. 10.1021/acsmedchemlett.6b00027. [PDB: 5i7u] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| McTigue, M.; Deng, Y.-L.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).. Protein Data Bank: 5a9u. |
CMCF-ID |
PDB Deposition |
Health |
| Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Sheriff, S. (2016). Structure of the extracellular domain of the CD40 in complex with 3H56-5 DAB. Protein Data Bank: 5dmj. |
CMCF-ID |
PDB Deposition |
Health |
| Sheriff, S. (2016). Structure of the extracellular domain of the CD40 in complex with CHI220 FAB. Protein Data Bank: 5dmi. |
CMCF-ID |
PDB Deposition |
Health |
| Yamniuk, Aaron P.; Suri, Anish; Krystek, Stanley R.; Tamura, James; Ramamurthy, Vidhyashankar et al. (2016). Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. Journal of Molecular Biology 428(14) , 2860-2879. 10.1016/j.jmb.2016.05.014. [PDB: 5dmi, 5dmj] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Vinogradova, Maia; Gehling, Victor S; Gustafson, Amy; Arora, Shilpi; Tindell, Charles A et al. (2016). An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nature Chemical Biology 12(7) , 531-538. 10.1038/nchembio.2085. [PDB: 5ceh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hobbs, Joanne K.; Lee, Seunghyae M.; Robb, Melissa; Hof, Fraser; Barr, Christopher et al. (2016). KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America 113(22) , 6188-6193. 10.1073/pnas.1524214113. [PDB: 5fpx, 5fpz] |
CMCF-ID |
Peer-Reviewed Article |
Materials |