Publication Beamlines Strategic Pillar
Kwan, David H.; Constantinescu, Iren; Chapanian, Rafi; Higgins, Melanie A.; Kötzler, Miriam P et al. (2015). Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution. Journal of the American Chemical Society 137(17) , 5695-5705. 10.1021/ja5116088. [PDB: 4d6c, 4d6d, 4d6e, 4d6g] CMCF-BM, CMCF-ID Health
Adamiak, Paul; Calmettes, Charles; Moraes, Trevor F.; Schryvers, Anthony B. (2015). Patterns of structural and sequence variation within isotype lineages of the Neisseria meningitidis transferrin receptor system. MicrobiologyOpen 4(3) , 491-504. 10.1002/mbo3.254. [PDB: 4qq1] CMCF-BM Health
Chan, Anson C.K.; Blair, Kris M.; Liu, Yanjie; Frirdich, Emilisa; Gaynor, Erin C. et al. (2015). Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. Journal of Biological Chemistry 290(6) , jbc.M114.624734. 10.1074/jbc.m114.624734. [PDB: 4wck, 4wcl, 4wcm, 4wcn] CMCF-BM, CMCF-ID Health
Bergeron, Julien R.C.; Worrall, Liam J.; De, Soumya; Sgourakis, Nikolaos G.; Cheung, Adrienne H. et al. (2015). The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure 23(1) , 161-172. 10.1016/j.str.2014.10.021. [PDB: 4oyc, 4w4m] CMCF-BM Health
Sobhanifar, Solmaz; Worrall, Liam James; Gruninger, Robert J.; Wasney, Gregory A.; Blaukopf, Markus et al. (2015). Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid α-glycosyltransferase. Proceedings of the National Academy of Sciences of the United States of America 112(6) , E576-E585. 10.1073/pnas.1418084112. [PDB: 4x6l, 4x7m, 4x7p, 4x7r] CMCF-BM Health
White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A. et al. (2015). Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. ACS Chemical Biology 10(5) , 1198-1208. 10.1021/cb500757u. [PDB: 4ofb] CMCF-BM, CMCF-ID Health
Sanhueza, Carlos A.; Cartmell, Jonathan; El-Hawiet, Amr; Szpacenko, Adam; Kitova, Elena N. et al. (2015). Evaluation of a focused virtual library of heterobifunctional ligands for Clostridium difficile toxins. Organic and Biomolecular Chemistry 13(1) , 283-298. 10.1039/c4ob01838a. CMCF-BM Health
Badea, Ildiko; Poorghorban, Masoomeh; Das, Umashankar; Alaidi, Osama; Chitanda, Jackson et al. (2015). Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity. International Journal of Nanomedicine , 503-515. 10.2147/ijn.s70828. CMCF-BM, MID-IR Health
King, Dustin T.; King, Andrew M.; Lal, Sarah M.; Wright, Gerard D.; Strynadka, Natalie C. J. et al. (2015). Molecular Mechanism of Avibactam-Mediated β-Lactamase Inhibition. ACS Infectious Diseases 1(4) , 175-184. 10.1021/acsinfecdis.5b00007. [PDB: 4s2i, 4s2j, 4s2k, 4s2n, 4s2o, 4s2p] CMCF-BM Health
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. [PDB: 4c1r, 4c1s] CMCF-BM, CMCF-ID Health
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] CMCF-BM, CMCF-ID Health
Ivanochko, Danton; Miura, Kazutoyo; Hailemariam, Sophia; Ravichandran, Rashmi; Song, Yiting et al. (2026). A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity. Nature Communications . 10.1038/s41467-026-68761-1. CMCF-ID Health
Haines, Eric; Burke, Michael; Catterall, Rachel; De Jesus, Victor; Hidalgo, Daniel et al. (2026). The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers. Nature Cancer . 10.1038/s43018-025-01081-3. [PDB: 9ecu] CMCF-ID Health
Kwon, Min Chul; Thuring, Jan Willem; Querolle, Olivier; Dai, Xuedong; Verhulst, Tinne et al. (2024). Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias. Blood 144(11) , 1206-1220. 10.1182/blood.2023022480. [PDB: 9z4x] CMCF-ID Health
Kimani, Serah W.; Noureldin, Mahmoud; Wilson, Brian; Hoffer, Laurent; Green, Stuart R. et al. (2025). OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Communications Biology 8(1) . 10.1038/s42003-025-08491-0. [PDB: 9yv4] CMCF-ID Health