Publication Beamlines Strategic Pillar
Sauvé, Véronique; Sung, George; Soya, Naoto; Kozlov, Guennadi; Blaimschein, Nina et al. (2018). Mechanism of parkin activation by phosphorylation. Nature Structural and Molecular Biology 25(7) , 623-630. 10.1038/s41594-018-0088-7. [PDB: 6djw, 6djx] CMCF-ID Health
Scally, Stephen W.; McLeod, Brandon; Bosch, Alexandre; Miura, Kazutoyo; Liang, Qi et al. (2017). Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25. Nature Communications 8(1) . 10.1038/s41467-017-01924-3. [PDB: 6azz, 6b08, 6b0a, 6b0e, 6b0g, 6b0h] CMCF-ID Health
Scally, Stephen W.; Murugan, Rajagopal; Bosch, Alexandre; Triller, Gianna; Costa, Giulia et al. (2017). Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection. Journal of Experimental Medicine 215(1) , 63-75. 10.1084/jem.20170869. [PDB: 6b0s, 6b0w] CMCF-ID Health
Scapin, Giovanna; Yang, Xiaoyu; Prosise, Winifred W; McCoy, Mark; Reichert, Paul et al. (2015). Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab. Nature Structural and Molecular Biology 22(12) , 953-958. 10.1038/nsmb.3129. [PDB: 5dk3] CMCF-ID Health
Schenkel, Laurie B.; Molina, Jennifer R.; Swinger, Kerren K.; Abo, Ryan; Blackwell, Danielle J. et al. (2021). A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants. Cell Chemical Biology 28(8) . 10.1016/j.chembiol.2021.02.010. [PDB: 6we2] CMCF-ID Health
Scholl, Connor L.; Tsuda, Sakae; Graham, Laurie A.; Davies, Peter L. (2021). Crystal waters on the nine polyproline type II helical bundle springtail antifreeze protein from Granisotoma rainieri match the ice lattice. FEBS Journal 288(14) . 10.1111/febs.15717. [PDB: 7jjv] CMCF-ID Health
Schrag, Joseph D.; Picard, Marie-Ève; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason et al. (2019). Binding symmetry and surface flexibility mediate antibody self-association. mAbs 11(7) , 1-19. 10.1080/19420862.2019.1632114. [PDB: 6mxr, 6mxs, 6my4, 6my5] CMCF-ID Health
Schroeter, Kurt L.; Rolfe, Nicolas; Forrester, Taylor J.B.; Kimber, Matthew S.; Seah, Stephen Y.K. et al. (2024). Shy is a proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain. Journal of Biological Chemistry 300(8) , 107509. 10.1016/j.jbc.2024.107509. [PDB: 8vwr] CMCF-ID Health
Schulte, Christie A.; Deaton, David N.; Diaz, Elsie; Do, Young; Gampe, Robert T. et al. (2021). A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors. Bioorganic and Medicinal Chemistry Letters 47, 128113. 10.1016/j.bmcl.2021.128113. [PDB: 7jr6] CMCF-ID Health
Scott, William; Lowrance, Brian; Anderson, Alexander C.; Weadge, Joel T. (2020). Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. PLoS ONE 15(12) , e0242686. 10.1371/journal.pone.0242686. [PDB: 6uje, 6ujf] CMCF-ID Health
Sengupta, Shomit; Giaime, Emilie; Narayan, Sridhar; Hahm, Seung; Howell, Jessica et al. (2019). Discovery of NV-5138, the first selective Brain mTORC1 activator. Scientific Reports 9(1) , 4107. 10.1038/s41598-019-40693-5. [PDB: 6n0m] CMCF-ID Health
Shah, Megha; Taylor, Véronique L.; Bona, Diane; Tsao, Yvonne; Stanley, Sabrina Y. et al. (2021). A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa. Molecular Cell 81(3) , 571-583.e6. 10.1016/j.molcel.2020.12.011. [PDB: 6v7u, 6v7v] CMCF-ID Health
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] CMCF-ID Health
Shen, Yi; Wen, Yurong; Sposini, Silvia; Vishwanath, Anjali Amrapali; Abdelfattah, Ahmed S. et al. (2023). Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sensors . 10.1021/acssensors.3c00484. [PDB: 7yv3, 7yv5] CMCF-ID Health
Shin, Youngsook; Suchomel, Julia; Cardozo, Mario; Duquette, Jason; He, Xiao et al. (2015). Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors. Journal of Medicinal Chemistry 59(1) , 431-447. 10.1021/acs.jmedchem.5b01651. [PDB: 5eds] CMCF-ID Health