Publication Beamlines Strategic Pillar
Murase, Tomohiko; Eugenio, Luiz; Schorr, Melissa; Hussack, Greg; Tanha, Jamshid et al. (2014). Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile. Journal of Biological Chemistry 289(4) , 2331-2343. 10.1074/jbc.m113.505917. [PDB: 4nbx, 4nby, 4nc1] CMCF-BM Health
Maynard, Andrew; Crosby, Renae M.; Ellis, Byron; Hamatake, Robert; Hong, Zhi et al. (2013). Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. Journal of Medicinal Chemistry 57(5) , 1902-1913. 10.1021/jm400317w. [PDB: 4khr] CMCF-ID Health
Azoitei, Mihai L.; Ban, Yih-En Andrew; Julien, Jean-Philippe; Bryson, Steve; Schroeter, Alexandria et al. (2012). Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope. Journal of Molecular Biology 415(1) , 175-192. 10.1016/j.jmb.2011.10.003. [PDB: 3rhu] CMCF-ID Health
Oh, Angela; Ho, Yen-Ching; Zak, Mark; Liu, Yongbo; Chen, Xukun et al. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. ChemBioChem 15(8) , 1121-1130. 10.1002/cbic.201402023. [PDB: 4o0z, 4o10] CMCF-ID Health
Trempe, Jean-François; Sauvé, Véronique; Grenier, Karl; Seirafi, Marjan; Tang, Matthew Y. et al. (2013). Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation. Science 340(6139) , 1451-1455. 10.1126/science.1237908. [PDB: 4k7d] CMCF-ID Health
Bertwistle, Drew; Vogt, Linda; Aamudalapalli, Hari Babu; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Purification, crystallization and room-temperature X-ray diffraction of inositol dehydrogenase LcIDH2 fromLactobacillus caseiBL23. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(7) , 979-983. 10.1107/s2053230x14011595. CMCF-ID Health
King, Dustin T.; Worrall, Liam J.; Gruninger, Robert; Strynadka, Natalie C. J. (2012). New Delhi Metallo-β-Lactamase: Structural Insights into β-Lactam Recognition and Inhibition. Journal of the American Chemical Society 134(28) , 11362-11365. 10.1021/ja303579d. [PDB: 4exy, 4ey2, 4eyb, 4eyf, 4eyl] CMCF-BM, CMCF-ID Health
Awad, Mark M.; Katayama, Ryohei; McTigue, Michele; Liu, Wei; Deng, Ya-Li et al. (2013). Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1. New England Journal of Medicine 368(25) , 2395-2401. 10.1056/nejmoa1215530. [PDB: 3zbf] CMCF-ID Health
van Straaten, Karin E.; Routier, Françoise H.; Sanders, David A.R. (2012). Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus. Journal of Biological Chemistry 287(14) , 10780-10790. 10.1074/jbc.m111.322974. [PDB: 3uka, 3ukf, 3ukh, 3ukk, 3ukl, 3ukp, 3ukq] CMCF-ID Health
Amunugama, Ravindra; He, Yujiong; Willcox, Smaranda; Forties, Robert A.; Shim, Kang-Sup et al. (2012). RAD51 Protein ATP Cap Regulates Nucleoprotein Filament Stability. Journal of Biological Chemistry 287(12) , 8724-8736. 10.1074/jbc.m111.239426. [PDB: 3ntu] CMCF-ID Health
Leung, Charles Chung Yun; Sun, Luxin; Gong, Zihua; Burkat, Michael; Edwards, Ross et al. (2013). Structural Insights into Recognition of MDC1 by TopBP1 in DNA Replication Checkpoint Control. Structure 21(8) , 1450-1459. 10.1016/j.str.2013.06.015. [PDB: 3ueo] CMCF-ID Health
Gomery, Kathryn; Müller-Loennies, Sven; Brooks, Cory L.; Brade, Lore; Kosma, Paul et al. (2012). Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proceedings of the National Academy of Sciences of the United States of America 109(51) , 20877-20882. 10.1073/pnas.1209253109. [PDB: 3v0w] CMCF-ID Health
Burkinshaw, Brianne J.; Prehna, Gerd; Worrall, Liam J.; Strynadka, Natalie C.J. (2012). Structure of Salmonella Effector Protein SopB N-terminal Domain in Complex with Host Rho GTPase Cdc42. Journal of Biological Chemistry 287(16) , 13348-13355. 10.1074/jbc.m111.331330. [PDB: 4did] CMCF-ID Health
Lin, Yih-Shyan; Park, Jaeok; De Schutter, Joris W.; Huang, Xian Fang; Berghuis, Albert M. et al. (2012). Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. Journal of Medicinal Chemistry 55(7) , 3201-3215. 10.1021/jm201657x. [PDB: 4dem] CMCF-ID Health
Thi, Nhung Nguyen; Offen, Wendy A.; Shareck, François; Davies, Gideon J.; Doucet, Nicolas et al. (2014). Structure and Activity of the Streptomyces coelicolor A3(2) β-N-Acetylhexosaminidase Provides Further Insight into GH20 Family Catalysis and Inhibition. Biochemistry 53(11) , 1789-1800. 10.1021/bi401697j. [PDB: 4c7f] CMCF-ID Health