Publication Beamlines Strategic Pillar
Jones, Michael D.; Chan, Anson C. K.; Nomellini, John F.; Murphy, Michael E. P.; Smit, John et al. (2016). Surface-layer protein fromCaulobacter crescentus: expression, purification and X-ray crystallographic analysis. Acta Crystallographica Section F:Structural Biology Communications 72(9) , 677-680. 10.1107/s2053230x16011638. CMCF-ID Health
Juang, Yu-Chi; Landry, Marie-Claude; Sanches, Mario; Vittal, Vinayak; Leung, Charles C.Y. et al. (2012). OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Molecular Cell 45(3) , 384-397. 10.1016/j.molcel.2012.01.011. [PDB: 4ddg] CMCF-ID Health
Julien, Jean-Philippe; Cupo, Albert; Sok, Devin; Stanfield, Robyn L.; Lyumkis, Dmitry et al. (2013). Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer. Science 342(6165) , 1477-1483. 10.1126/science.1245625. CMCF-BM, CMCF-ID Health
Juvvadi, Praveen R.; Fox, David; Bobay, Benjamin G.; Hoy, Michael J.; Gobeil, Sophie M. C. et al. (2019). Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nature Communications 10(1) . 10.1038/s41467-019-12199-1. [PDB: 6tz7] CMCF-ID Health
Kallander, Lara S.; Washburn, David; Hilfiker, Mark A.; Eidam, Hilary Schenck; Lawhorn, Brian G. et al. (2018). Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1. ACS Medicinal Chemistry Letters 9(7) , 736-740. 10.1021/acsmedchemlett.8b00173. [PDB: 6bsm] CMCF-ID Health
Kalliokoski, Tuomo; Kettunen, Henna; Kumpulainen, Esa; Kettunen, Emilia; Thieulin-Pardo, Gabriel et al. (2023). Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorganic and Medicinal Chemistry Letters 94, 129450. 10.1016/j.bmcl.2023.129450. [PDB: 8p1t, 8p1v] CMCF-ID Health
Kalynych, Sergei; Cherney, Maia; Bostina, Mihnea; Rouiller, Isabelle; Cygler, Miroslaw et al. (2014). Quaternary structure of WzzB and WzzE polysaccharide copolymerases. Protein Science 24(1) , 58-69. 10.1002/pro.2586. CMCF-ID Health
Kalynych, Sergei; Yao, Deqiang; Magee, James; Cygler, Miroslaw (2012). Structural Characterization of Closely Related O-antigen Lipopolysaccharide (LPS) Chain Length Regulators. Journal of Biological Chemistry 287(19) , 15696-15705. 10.1074/jbc.m112.354837. [PDB: 4e2c, 4e2h, 4e2l] CMCF-ID Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Keszei, Alexander F. A.; Tang, Xiaojing; McCormick, Craig; Zeqiraj, Elton; Rohde, John R. et al. (2014). Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase. Molecular and Cellular Biology 34(3) , 362-373. 10.1128/mcb.01360-13. [PDB: 4nkg] CMCF-ID Health
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] CMCF-ID Health
Keylor, Mitchell H.; Gulati, Anmol; Kattar, Solomon D.; Johnson, Rebecca E.; Chau, Ryan W. et al. (2021). Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. Journal of Medicinal Chemistry 65(1) , 838-856. 10.1021/acs.jmedchem.1c01968. [PDB: 7suh] CMCF-ID Health
Kgosisejo, Oarabile; Chen, Jian An; Grochulski, Pawel; Tanaka, Takuji (2017). Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships. Biochimica et Biophysica Acta - Proteins and Proteomics 1865(5) , 473-480. 10.1016/j.bbapap.2017.02.004. [PDB: 4zng, 6xmr, 7k3u, 7n02] CMCF-BM, CMCF-ID Health
Khalili Yazdi, Aliakbar; Namjoshi, Sarita; Hackett, Jesse; Ghonaim, Nour; Shilton, Brian H. et al. (2017). Characterization of a polypeptide-binding site in the DEAD Motor of the SecA ATPase. FEBS Letters 591(20) , 3378-3390. 10.1002/1873-3468.12832. [PDB: 5k94] CMCF-ID Health