Publication Beamlines Strategic Pillar
Strushkevich, Natallia; Gilep, Andrei A.; Shen, Limin; Arrowsmith, Cheryl H.; Edwards, Aled M. et al. (2013). Structural Insights into Aldosterone Synthase Substrate Specificity and Targeted Inhibition. Molecular Endocrinology 27(2) , 315-324. 10.1210/me.2012-1287. [PDB: 4dvq] CMCF-ID Health
Hong, Minsun; Lee, Peter S.; Hoffman, Ryan M. B.; Zhu, Xueyong; Krause, Jens C. et al. (2013). Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. Journal of Virology 87(22) , 12471-12480. 10.1128/jvi.01388-13. [PDB: 4m5z] CMCF-ID Health
Wheatley, Robert W.; Lo, Summie; Jancewicz, Larisa J.; Dugdale, Megan L.; Huber, Reuben E. et al. (2013). Structural Explanation for Allolactose (lac Operon Inducer) Synthesis by lacZ β-Galactosidase and the Evolutionary Relationship between Allolactose Synthesis and the lac Repressor. Journal of Biological Chemistry 288(18) , 12993-13005. 10.1074/jbc.m113.455436. [PDB: 4duw, 4dux] CMCF-BM Health
Jha, Vikash; Donald, Lynda J.; Loewen, Peter C. (2012). Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage. Archives of Biochemistry and Biophysics 525(2) , 207-214. 10.1016/j.abb.2011.11.022. [PDB: 3ttt, 3ttv, 3ttw, 3ttx] CMCF-ID Health
Leung, Chun Yuen; Park, Jaeok; De Schutter, Joris W.; Sebag, Michael; Berghuis, Albert M. et al. (2013). Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. Journal of Medicinal Chemistry 56(20) , 7939-7950. 10.1021/jm400946f. [PDB: 4jvj, 4l2x] CMCF-ID Health
Dalrymple, Sean A.; Ko, John; Sheoran, Inder; Kaminskyj, Susan G. W.; Sanders, David A. R. et al. (2013). Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase. PLoS ONE 8(10) , e76803. 10.1371/journal.pone.0076803. [PDB: 4lis] CMCF-ID Health
Zhang, Xiaolu Linda; Tibbits, Glen F.; Paetzel, Mark (2013). The structure of cardiac troponin C regulatory domain with bound Cd2+reveals a closed conformation and unique ion coordination. Acta Crystallographica Section D Biological Crystallography 69(5) , 722-734. 10.1107/s0907444913001182. [PDB: 3sd6, 4gje, 4gjf, 4gjg] CMCF-BM, CMCF-ID Health
Hehemann, Jan-Hendrik; Smyth, Leo; Yadav, Anuj; Vocadlo, David J.; Boraston, Alisdair B. et al. (2012). Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight into the Degradation (of a Polysaccharide from) Red Seaweeds. Journal of Biological Chemistry 287(17) , 13985-13995. 10.1074/jbc.m112.345645. [PDB: 4ak7] CMCF-ID Health
Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten; Derking, Ronald; Falkowska, Emilia et al. (2014). Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity 40(5) , 669-680. 10.1016/j.immuni.2014.04.008. [PDB: 4nug] CMCF-ID Health
Campbell, Stephen J.; Edwards, Ross A.; Leung, Charles C.Y.; Neculai, Dante; Hodge, Curtis D. et al. (2012). Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation. Journal of Biological Chemistry 287(28) , 23900-23910. 10.1074/jbc.m112.359653. CMCF-ID Health
Zheng, Hongyan; Bertwistle, Drew; Sanders, David A. R.; Palmer, David R. J. (2013). Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist. Biochemistry 52(34) , 5876-5883. 10.1021/bi400821s. [PDB: 4l8v, 4l9r] CMCF-ID Health
Nakamura, Gerald; Chai, Ning; Park, Summer; Chiang, Nancy; Lin, Zhonghua et al. (2013). An In Vivo Human-Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Influenza A Antibodies. Cell Host and Microbe 14(1) , 93-103. 10.1016/j.chom.2013.06.004. [PDB: 4kvn] CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Vocadlo, David J.; Mark, Brian L. et al. (2012). Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chemistry & Biology 19(11) , 1471-1482. 10.1016/j.chembiol.2012.09.016. [PDB: 4gvf, 4gvg, 4gvh, 4gyj, 4gyk] CMCF-ID Health
Korbas, Malgorzata; MacDonald, Tracy C.; Pickering, Ingrid J.; George, Graham N.; Krone, Patrick H. et al. (2011). Chemical Form Matters: Differential Accumulation of Mercury Following Inorganic and Organic Mercury Exposures in Zebrafish Larvae. ACS Chemical Biology 7(2) , 411-420. 10.1021/cb200287c. CLS-APS Health
Gonzalez-Lopez de Turiso, Felix; Sun, Daqing; Rew, Yosup; Bartberger, Michael D.; Beck, Hilary P. et al. (2013). Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors. Journal of Medicinal Chemistry 56(10) , 4053-4070. 10.1021/jm400293z. [PDB: 4jwr] CMCF-ID Health