Publication Beamlines Strategic Pillar
Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] CMCF-BM Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. [PDB: 6mne] CMCF-BM, CMCF-ID Health
Little, Dustin J.; Coombes, Brian K. (2018). Molecular basis for CesT recognition of type III secretion effectors in enteropathogenic Escherichia coli. PLoS Pathogens 14(8) , e1007224. 10.1371/journal.ppat.1007224. [PDB: 5wez] CMCF-BM Health
Liu, Yanjie; Frirdich, Emilisa; Taylor, Jennifer A.; Chan, Anson C. K.; Blair, Kris M. et al. (2016). A Bacterial Cell Shape-Determining Inhibitor. ACS Chemical Biology 11(4) , 981-991. 10.1021/acschembio.5b01039. [PDB: 5d2r] CMCF-BM Health
Lizak, Christian; Worrall, Liam J.; Baumann, Lars; Pfleiderer, Moritz M.; Volkers, Gesa et al. (2017). X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Scientific Reports 7(1) . 10.1038/s41598-017-05627-z. [PDB: 5wc6, 5wcn, 5wd7] CMCF-BM, CMCF-ID Health
Loewen, Peter C.; Switala, Jacek; Wells, James P.; Huang, Fang; Zara, Anthony T. et al. (2018). Structure and function of a lignostilbene-α,β-dioxygenase orthologue from Pseudomonas brassicacearum. BMC Biochemistry 19(1) . 10.1186/s12858-018-0098-4. [PDB: 5v2d] CMCF-BM Health
Lorente Cobo, Neil; Sibinelli-Sousa, Stephanie; Biboy, Jacob; Vollmer, Waldemar; Bayer-Santos, Ethel et al. (2022). Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold. Journal of Biological Chemistry 298(11) , 102556. 10.1016/j.jbc.2022.102556. [PDB: 7uo3, 7uo8] CMCF-BM Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] CMCF-BM Health
Mabanglo, Mark F.; Leung, Elisa; Vahidi, Siavash; Seraphim, Thiago V.; Eger, Bryan T. et al. (2019). ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Communications Biology 2(1) . 10.1038/s42003-019-0656-3. [PDB: 6naq, 6nb1] CMCF-BM Health