Publication Beamlines Strategic Pillar
King, Andrew M.; King, Dustin T.; French, Shawn; Brouillette, Eric; Asli, Abdelhamid et al. (2016). Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chemical Biology 11(4) , 864-868. 10.1021/acschembio.5b00944. CMCF-ID Health
Kobylarz, Marek J.; Grigg, Jason C.; Liu, Yunan; Lee, Mathew S. F.; Heinrichs, David E. et al. (2016). Deciphering the Substrate Specificity of SbnA, the Enzyme Catalyzing the First Step in Staphyloferrin B Biosynthesis. Biochemistry 55(6) , 927-939. 10.1021/acs.biochem.5b01045. CMCF-BM, CMCF-ID Health
Lee, Samuel K.; Shanmughapriya, Santhanam; Mok, Mac C.Y.; Dong, Zhiwei; Tomar, Dhanendra et al. (2016). Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chemical Biology 23(9) , 1157-1169. 10.1016/j.chembiol.2016.07.012. CMCF-ID Health
Lyons, Bronwyn; Ravulapalli, Ravikiran; Lanoue, Jason; Lugo, Miguel R.; Dutta, Debajyoti et al. (2016). Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. Journal of Biological Chemistry 291(21) , 11198-11215. 10.1074/jbc.m115.707653. CMCF-ID Health
Mann, Evan; Mallette, Evan; Clarke, Bradley R.; Kimber, Matthew S.; Whitfield, Chris et al. (2016). The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate. Journal of Biological Chemistry 291(18) , 9748-9761. 10.1074/jbc.m116.719344. CMCF-BM Health
Mazurkewich, Scott; Brott, Ashley S.; Kimber, Matthew S.; Seah, Stephen Y.K. (2016). Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440. Journal of Biological Chemistry 291(14) , 7669-7686. 10.1074/jbc.m115.682054. CMCF-BM, CMCF-ID Health
Movahedin, Mohammadreza; Brooks, Teresa M; Supekar, Nitin T; Gokanapudi, Naveen; Boons, Geert-Jan et al. (2016). Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen. Glycobiology , 677-687. 10.1093/glycob/cww131. CMCF-ID Health
Myers, Cullen L.; Li, Franco K.K.; Koo, Byoung-Mo; El-Halfawy, Omar M.; French, Shawn et al. (2016). Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. Journal of Biological Chemistry 291(50) , 26066-26082. 10.1074/jbc.m116.760447. CMCF-BM, CMCF-ID Health
Noach, Ilit; Pluvinage, Benjamin; Laurie, Cassandra; Abe, Kento T.; Alteen, Matthew G. et al. (2016). The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium perfringens. Journal of Molecular Biology 428(16) , 3253-3265. 10.1016/j.jmb.2016.03.020. CMCF-ID Health
Ovchinnikova, Olga G.; Mallette, Evan; Koizumi, Akihiko; Lowary, Todd L.; Kimber, Matthew S. et al. (2016). Bacterial β-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99). Proceedings of the National Academy of Sciences of the United States of America 113(22) , 3120-3129. 10.1073/pnas.1603146113. CMCF-BM, CMCF-ID Health
Reimer, Janice M.; Aloise, Martin N.; Harrison, Paul M.; Martin Schmeing, T. (2016). Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase. Nature 529(7585) , 239-242. 10.1038/nature16503. CMCF-ID Health
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. CMCF-ID Health
Skovpen, Yulia V.; Conly, Cuylar J. T.; Sanders, David A. R.; Palmer, David R. J. (2016). Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. Journal of the American Chemical Society 138(6) , 2014-2020. 10.1021/jacs.5b12695. CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. CMCF-BM, CMCF-ID Health
Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. CMCF-ID Health