Zamyatkin, Dmitry F.; Parra, Francisco; Machín, Ángeles; Grochulski, Pawel; Ng, Kenneth K.-S. et al. (2009). Binding of 2′-Amino-2′-Deoxycytidine-5′-Triphosphate to Norovirus Polymerase Induces Rearrangement of the Active Site. Journal of Molecular Biology 390(1) , 10-16. 10.1016/j.jmb.2009.04.069. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Yuchi, Zhiguang; Lau, Kelvin; Van Petegem, Filip (2012). Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain. Structure 20(7) , 1201-1211. 10.1016/j.str.2012.04.015. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Yang, Yuhong; Xu, Yuanyuan; Yue, Yuan; Wang, Heng; Cui, Yumeng et al. (2021). Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. ACS Chemical Biology 17(1) , 39-53. 10.1021/acschembio.1c00394. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Yamniuk, Aaron P.; Suri, Anish; Krystek, Stanley R.; Tamura, James; Ramamurthy, Vidhyashankar et al. (2016). Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. Journal of Molecular Biology 428(14) , 2860-2879. 10.1016/j.jmb.2016.05.014. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Xu, Yufei; Xu, Chao; Kato, Akiko; Tempel, Wolfram; Abreu, Jose Garcia et al. (2012). Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development. Cell 151(6) , 1200-1213. 10.1016/j.cell.2012.11.014. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wu, Hong; Zeng, Hong; Lam, Robert; Tempel, Wolfram; Amaya, Maria F. et al. (2011). Structural and Histone Binding Ability Characterizations of Human PWWP Domains. PLoS ONE 6(6) , e18919. 10.1371/journal.pone.0018919. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wrobleski, Stephen T.; Moslin, Ryan; Lin, Shuqun; Zhang, Yanlei; Spergel, Steven et al. (2019). Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. Journal of Medicinal Chemistry 62(20) . 10.1021/acs.jmedchem.9b00444. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wong, Alan H.M.; Zhou, Dongxia; Rini, James M. (2012). The X-ray Crystal Structure of Human Aminopeptidase N Reveals a Novel Dimer and the Basis for Peptide Processing. Journal of Biological Chemistry 287(44) , 36804-36813. 10.1074/jbc.m112.398842. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wiseman, Ben; Carpena, Xavi; Feliz, Miguel; Donald, Lynda J.; Pons, Miquel et al. (2010). Isonicotinic Acid Hydrazide Conversion to Isonicotinyl-NAD by Catalase-peroxidases. Journal of Biological Chemistry 285(34) , 26662-26673. 10.1074/jbc.m110.139428. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Whitesell, Luke; Robbins, Nicole; Huang, David S.; McLellan, Catherine A.; Shekhar-Guturja, Tanvi et al. (2019). Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nature Communications 10(1) , 402. 10.1038/s41467-018-08248-w. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wheatley, Robert W.; Lo, Summie; Jancewicz, Larisa J.; Dugdale, Megan L.; Huber, Reuben E. et al. (2013). Structural Explanation for Allolactose (lac Operon Inducer) Synthesis by lacZ β-Galactosidase and the Evolutionary Relationship between Allolactose Synthesis and the lac Repressor. Journal of Biological Chemistry 288(18) , 12993-13005. 10.1074/jbc.m113.455436. |
CMCF-BM |
Peer-Reviewed Article |
Health |
Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry 222, 113584. 10.1016/j.ejmech.2021.113584. |
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