Publication Beamlines Strategic Pillar
Lizak, Christian; Worrall, Liam J.; Baumann, Lars; Pfleiderer, Moritz M.; Volkers, Gesa et al. (2017). X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Scientific Reports 7(1) . 10.1038/s41598-017-05627-z. CMCF-BM, CMCF-ID Health
Zhao, Jianhua; Beyrakhova, Ksenia; Liu, Yao; Alvarez, Claudia P.; Bueler, Stephanie A. et al. (2017). Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathogens 13(6) , e1006394. 10.1371/journal.ppat.1006394. CMCF-BM, CMCF-ID Health
Zhang, Wei; Bailey-Elkin, Ben A.; Knaap, Robert C. M.; Khare, Baldeep; Dalebout, Tim J. et al. (2017). Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathogens 13(5) , e1006372. 10.1371/journal.ppat.1006372. CMCF-BM, CMCF-ID Health
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. CMCF-BM Health
Myers, Cullen L.; Li, Franco K.K.; Koo, Byoung-Mo; El-Halfawy, Omar M.; French, Shawn et al. (2016). Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. Journal of Biological Chemistry 291(50) , 26066-26082. 10.1074/jbc.m116.760447. CMCF-BM, CMCF-ID Health
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. CMCF-BM, CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. CMCF-BM, CMCF-ID Health
Torres, Miguel A.; Hoffarth, Elesha; Eugenio, Luiz; Savtchouk, Julia; Chen, Xue et al. (2016). Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. Journal of Biological Chemistry 291(45) , 23403-23415. 10.1074/jbc.m116.747261. CMCF-BM Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. CMCF-BM, CMCF-ID Health
Ovchinnikova, Olga G.; Mallette, Evan; Koizumi, Akihiko; Lowary, Todd L.; Kimber, Matthew S. et al. (2016). Bacterial β-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99). Proceedings of the National Academy of Sciences of the United States of America 113(22) , 3120-3129. 10.1073/pnas.1603146113. CMCF-BM, CMCF-ID Health
Mann, Evan; Mallette, Evan; Clarke, Bradley R.; Kimber, Matthew S.; Whitfield, Chris et al. (2016). The Klebsiella pneumoniae O12 ATP-binding Cassette (ABC) Transporter Recognizes the Terminal Residue of Its O-antigen Polysaccharide Substrate. Journal of Biological Chemistry 291(18) , 9748-9761. 10.1074/jbc.m116.719344. CMCF-BM Health
Volkers, Gesa; Worrall, Liam J; Kwan, David H; Yu, Ching-Ching; Baumann, Lars et al. (2015). Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nature Structural and Molecular Biology 22(8) , 627-635. 10.1038/nsmb.3060. CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. CMCF-BM, CMCF-ID Health
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. CMCF-BM, CMCF-ID Health
Hanan, Emily J.; Baumgardner, Matt; Bryan, Marian C.; Chen, Yuan; Eigenbrot, Charles et al. (2016). 4-Aminoindazolyl-dihydrofuro[3,4- d ]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic and Medicinal Chemistry Letters 26(2) , 534-539. 10.1016/j.bmcl.2015.11.078. CMCF-BM Health