Publication Beamlines Strategic Pillar
Simonetta, Kyle R.; Taygerly, Joshua; Boyle, Kathleen; Basham, Stephen E.; Padovani, Chris et al. (2019). Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications 10(1) , 1402. 10.1038/s41467-019-09358-9. CMCF-ID Health
Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. CMCF-ID Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. CMCF-BM, CMCF-ID Health
Pluvinage, Benjamin; Fillo, Alexander; Massel, Patricia; Boraston, Alisdair B. (2017). Structural Analysis of a Family 81 Glycoside Hydrolase Implicates Its Recognition of β-1,3-Glucan Quaternary Structure. Structure 25(9) , 1348-1359.e3. 10.1016/j.str.2017.06.019. CMCF-ID Health
Mangat, Chand S.; Vadlamani, Grishma; Holicek, Viktor; Chu, Mitchell; Larmour, Veronica L. C. et al. (2019). Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam. Antimicrobial Agents and Chemotherapy 63(4) . 10.1128/aac.02112-18. CMCF-BM, CMCF-ID Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. CMCF-BM, CMCF-ID Health
Whitesell, Luke; Robbins, Nicole; Huang, David S.; McLellan, Catherine A.; Shekhar-Guturja, Tanvi et al. (2019). Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nature Communications 10(1) , 402. 10.1038/s41467-018-08248-w. CMCF-ID Health
Marshall, Jeremy D.S.; Mellor, Paul; Ruan, Xuan; Whitecross, Dielle E.; Moore, Stanley A. et al. (2018). Insight into the PTEN - p85α interaction and lipid binding properties of the p85α BH domain. Oncotarget 9(97) , 36975-36992. 10.18632/oncotarget.26432. CMCF-BM, CMCF-ID Health
Gytz, Heidi; Liang, Jason; Liang, Yingke; Gorelik, Alexei; Illes, Katalin et al. (2019). The structure of mammalian β‐mannosidase provides insight into β‐mannosidosis and nystagmus. FEBS Journal 286(7) . 10.1111/febs.14731. CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L.; MacKenzie, C. Roger; Caveney, Nathanael et al. (2018). Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry 58(6) , 714-726. 10.1021/acs.biochem.8b00318. CMCF-ID Health
Raczynska, Joanna E.; Shabalin, Ivan G.; Minor, Wladek; Wlodawer, Alexander; Jaskolski, Mariusz et al. (2018). A close look onto structural models and primary ligands of metallo-β-lactamases. Drug Resistance Updates 40, 1-12. 10.1016/j.drup.2018.08.001. CMCF-BM Health
Ishiyama, Noboru; Sarpal, Ritu; Wood, Megan N.; Barrick, Samantha K.; Nishikawa, Tadateru et al. (2018). Force-dependent allostery of the α-catenin actin-binding domain controls adherens junction dynamics and functions. Nature Communications 9(1) . 10.1038/s41467-018-07481-7. CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. CMCF-BM, CMCF-ID Health
Huguenin-Dezot, Nicolas; Alonzo, Diego A.; Heberlig, Graham W.; Mahesh, Mohan; Nguyen, Duy P. et al. (2018). Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature 565(7737) , 112-117. 10.1038/s41586-018-0781-z. CMCF-ID Health
Kundu, Prasun; Semesi, Anthony; Jore, Matthijs M.; Morin, Merribeth J.; Price, Virginia L. et al. (2018). Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nature Communications 9(1) . 10.1038/s41467-018-06742-9. CMCF-ID Health