| Hobbs, Joanne K.; Lee, Seunghyae M.; Robb, Melissa; Hof, Fraser; Barr, Christopher et al. (2016). KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America 113(22) , 6188-6193. 10.1073/pnas.1524214113. |
CMCF-ID |
Peer-Reviewed Article |
Materials |
| Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caldwell, Shane J.; Huang, Yue; Berghuis, Albert M. (2016). Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2″)-Ia. Structure 24(6) , 935-945. 10.1016/j.str.2016.04.002. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gruninger, Robert J.; Cote, Chris; McAllister, Tim A.; Abbott, D. Wade (2016). Contributions of a unique β-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases. Biochemical Journal 473(7) , 839-849. 10.1042/bj20151153. |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| Bloudoff, Kristjan; Alonzo, Diego A.; Schmeing, T. Martin (2016). Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chemical Biology 23(3) , 331-339. 10.1016/j.chembiol.2016.02.012. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Noach, Ilit; Pluvinage, Benjamin; Laurie, Cassandra; Abe, Kento T.; Alteen, Matthew G. et al. (2016). The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium perfringens. Journal of Molecular Biology 428(16) , 3253-3265. 10.1016/j.jmb.2016.03.020. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lyons, Bronwyn; Ravulapalli, Ravikiran; Lanoue, Jason; Lugo, Miguel R.; Dutta, Debajyoti et al. (2016). Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. Journal of Biological Chemistry 291(21) , 11198-11215. 10.1074/jbc.m115.707653. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Jha, Vikash; Bian, Chuanbing; Xing, Guangxin; Ling, Hong (2016). Structure and mechanism of error-free replication past the major benzo[a]pyrene adduct by human DNA polymerase κ. Nucleic Acids Research 44(10) , 4957-4967. 10.1093/nar/gkw204. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ovchinnikova, Olga G.; Mallette, Evan; Koizumi, Akihiko; Lowary, Todd L.; Kimber, Matthew S. et al. (2016). Bacterial β-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99). Proceedings of the National Academy of Sciences of the United States of America 113(22) , 3120-3129. 10.1073/pnas.1603146113. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Leaver-Fay, Andrew; Froning, Karen J.; Atwell, Shane; Aldaz, Hector; Pustilnik, Anna et al. (2016). Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure 24(4) , 641-651. 10.1016/j.str.2016.02.013. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Materials |
| Getlik, Matthäus; Smil, David; Zepeda-Velázquez, Carlos; Bolshan, Yuri; Poda, Gennady et al. (2016). Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1). Journal of Medicinal Chemistry 59(6) , 2478-2496. 10.1021/acs.jmedchem.5b01630. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Skovpen, Yulia V.; Conly, Cuylar J. T.; Sanders, David A. R.; Palmer, David R. J. (2016). Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. Journal of the American Chemical Society 138(6) , 2014-2020. 10.1021/jacs.5b12695. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Chaudet, Marcia M.; Rose, David R. (2016). Suggested alternative starch utilization system from the human gut bacterium Bacteroides thetaiotaomicron. Biochemistry and Cell Biology 94(3) , 241-246. 10.1139/bcb-2016-0002. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Parker, Michelle L.; Penarete-Vargas, Diana M.; Hamilton, Phineas T.; Guérin, Amandine; Dubey, Jitender P. et al. (2015). Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair. Proceedings of the National Academy of Sciences of the United States of America 113(2) , 398-403. 10.1073/pnas.1515898113. |
CMCF-ID |
Peer-Reviewed Article |
Health |