Guo, Shuaiqi; Vance, Tyler D. R.; Zahiri, Hossein; Eves, Robert; Stevens, Corey et al. (2021). Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation. mBio 12(2) . 10.1128/mbio.00130-21. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Prasertanan, Theerawat; Palmer, David R.J.; Sanders, David A.R. (2021). Snapshots along the catalytic path of KabA, a PLP-dependent aminotransferase required for kanosamine biosynthesis in Bacillus cereus UW85. Journal of Structural Biology 213(2) , 107744. 10.1016/j.jsb.2021.107744. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Li, Franco K.K.; Gale, Robert T.; Petrotchenko, Evgeniy V.; Borchers, Christoph H.; Brown, Eric D. et al. (2021). Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis. Journal of Structural Biology 213(2) , 107733. 10.1016/j.jsb.2021.107733. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hu, Carol H.; Neissel Valente, Meriah W.; Halpern, O. Scott; Jusuf, Sutjano; Khan, Javed A. et al. (2021). Small molecule and macrocyclic pyrazole derived inhibitors of myeloperoxidase (MPO). Bioorganic and Medicinal Chemistry Letters 42, 128010. 10.1016/j.bmcl.2021.128010. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Mulligan, Vikram Khipple; Workman, Sean; Sun, Tianjun; Rettie, Stephen; Li, Xinting et al. (2021). Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1. Proceedings of the National Academy of Sciences of the United States of America 118(12) , e2012800118. 10.1073/pnas.2012800118. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Vatta, Maritza; Lyons, Bronwyn; Heney, Kayla A.; Lidster, Taylor; Merrill, A. Rod et al. (2021). Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies. Toxins 13(1) , 55. 10.3390/toxins13010055. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Lu, Xiaocen; Wen, Yurong; Zhang, Shuce; Zhang, Wei; Chen, Yilun et al. (2020). Improved Photocleavable Proteins with Faster and More Efficient Dissociation. Journal of Nanoparticle Research . 10.1101/2020.12.10.419556. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ferri, Elena; Le Thomas, Adrien; Wallweber, Heidi Ackerly; Day, Eric S.; Walters, Benjamin T. et al. (2020). Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature Communications 11(1) . 10.1038/s41467-020-19974-5. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Scott, William; Lowrance, Brian; Anderson, Alexander C.; Weadge, Joel T. (2020). Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. PLoS ONE 15(12) , e0242686. 10.1371/journal.pone.0242686. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Vance, Tyler D.R.; Ye, Qilu; Conroy, Brigid; Davies, Peter L. (2020). Essential role of calcium in extending RTX adhesins to their target. Journal of Structural Biology: X 4, 100036. 10.1016/j.yjsbx.2020.100036. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Stirling, Alexander J.; Gilbert, Stephanie E.; Conner, Megan; Mallette, Evan; Kimber, Matthew S. et al. (2020). A Key Glycine in Bacterial Steroid-Degrading Acyl-CoA Dehydrogenases Allows Flavin-Ring Repositioning and Modulates Substrate Side Chain Specificity. Biochemistry 59(42) , 4081-4092. 10.1021/acs.biochem.0c00568. |
CMCF-ID |
Peer-Reviewed Article |
Health |