| King, Dustin T.; Wasney, Gregory A.; Nosella, Michael; Fong, Anita; Strynadka, Natalie C.J. et al. (2017). Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B. Journal of Biological Chemistry 292(3) , 979-993. 10.1074/jbc.m116.718403. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara et al. (2016). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Myers, Cullen L.; Li, Franco K.K.; Koo, Byoung-Mo; El-Halfawy, Omar M.; French, Shawn et al. (2016). Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. Journal of Biological Chemistry 291(50) , 26066-26082. 10.1074/jbc.m116.760447. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Ulaganathan, ThirumalaiSelvi; Shi, Rong; Yao, Deqiang; Gu, Ruo-Xu; Garron, Marie-Line et al. (2016). Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III fromBacteroides thetaiotaomicron(BT4657). Glycobiology 27(2) , 176-187. 10.1093/glycob/cww096. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lee, Samuel K.; Shanmughapriya, Santhanam; Mok, Mac C.Y.; Dong, Zhiwei; Tomar, Dhanendra et al. (2016). Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chemical Biology 23(9) , 1157-1169. 10.1016/j.chembiol.2016.07.012. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hughes, Scott J.; Antoshchenko, Tetyana; Chen, Yun; Lu, Hua; Pizarro, Juan C. et al. (2016). Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. PLoS ONE 11(5) , e0154862. 10.1371/journal.pone.0154862. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Yamniuk, Aaron P.; Suri, Anish; Krystek, Stanley R.; Tamura, James; Ramamurthy, Vidhyashankar et al. (2016). Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope. Journal of Molecular Biology 428(14) , 2860-2879. 10.1016/j.jmb.2016.05.014. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Caldwell, Shane J.; Huang, Yue; Berghuis, Albert M. (2016). Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2″)-Ia. Structure 24(6) , 935-945. 10.1016/j.str.2016.04.002. |
CMCF-ID |
Peer-Reviewed Article |
Health |