Publication Beamlines Strategic Pillar
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. CMCF-BM, CMCF-ID Health
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. CMCF-BM, CMCF-ID Health
Dong, Cheng; Nakagawa, Reiko; Oyama, Kyohei; Yamamoto, Yusuke; Zhang, Weilian et al. (2020). Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. eLife 9. 10.7554/elife.58675. CMCF-BM, CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir et al. (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. CMCF-BM, CMCF-ID Health
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. CMCF-BM, CMCF-ID Health
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Gebai, Ahmad; Illes, Katalin; Piomelli, Daniele; Nagar, Bhushan et al. (2018). Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America 115(43) , E10032-E10040. 10.1073/pnas.1811759115. CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. CMCF-BM, CMCF-ID Health
Haji-Ghassemi, Omid; Yuchi, Zhiguang; Van Petegem, Filip (2019). The Cardiac Ryanodine Receptor Phosphorylation Hotspot Embraces PKA in a Phosphorylation-Dependent Manner. Molecular Cell 75(1) . 10.1016/j.molcel.2019.04.019. CMCF-BM Health
Hanan, Emily J.; Baumgardner, Matt; Bryan, Marian C.; Chen, Yuan; Eigenbrot, Charles et al. (2016). 4-Aminoindazolyl-dihydrofuro[3,4- d ]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic and Medicinal Chemistry Letters 26(2) , 534-539. 10.1016/j.bmcl.2015.11.078. CMCF-BM Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. CMCF-BM, CMCF-ID Health