Publication Beamlines Strategic Pillar
Leung, Chun Yuen; Park, Jaeok; De Schutter, Joris W.; Sebag, Michael; Berghuis, Albert M. et al. (2013). Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. Journal of Medicinal Chemistry 56(20) , 7939-7950. 10.1021/jm400946f. CMCF-ID Health
Zhang, Xiaolu Linda; Tibbits, Glen F.; Paetzel, Mark (2013). The structure of cardiac troponin C regulatory domain with bound Cd2+reveals a closed conformation and unique ion coordination. Acta Crystallographica Section D Biological Crystallography 69(5) , 722-734. 10.1107/s0907444913001182. CMCF-BM, CMCF-ID Health
Zheng, Hongyan; Bertwistle, Drew; Sanders, David A. R.; Palmer, David R. J. (2013). Converting NAD-Specific Inositol Dehydrogenase to an Efficient NADP-Selective Catalyst, with a Surprising Twist. Biochemistry 52(34) , 5876-5883. 10.1021/bi400821s. CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Vocadlo, David J.; Mark, Brian L. et al. (2012). Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chemistry & Biology 19(11) , 1471-1482. 10.1016/j.chembiol.2012.09.016. CMCF-ID Health
Amador, Fernando J.; Kimlicka, Lynn; Stathopulos, Peter B.; Gasmi-Seabrook, Geneviève M.C.; MacLennan, David H. et al. (2013). Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic α-Helix That Transitions to a β-Strand in a Mutant Linked with a Heritable Cardiomyopathy. Journal of Molecular Biology 425(21) , 4034-4046. 10.1016/j.jmb.2013.08.015. CMCF-ID Health
Petkun, Svetlana; Shi, Rong; Li, Yunge; Asinas, Abdalin; Munger, Christine et al. (2011). Structure of Hydrogenase Maturation Protein HypF with Reaction Intermediates Shows Two Active Sites. Structure 19(12) , 1773-1783. 10.1016/j.str.2011.09.023. CMCF-ID Health
Pfoh, Roland; Li, Angela; Chakrabarti, Nilmadhab; Payandeh, Jian; Pomès, Régis et al. (2012). Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proceedings of the National Academy of Sciences of the United States of America 109(46) , 18809-18814. 10.1073/pnas.1209018109. CMCF-ID Health
Sweeting, Braden; Brown, Eric; Khan, M. Qasim; Chakrabartty, Avijit; Pai, Emil F. et al. (2013). N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins. PLoS ONE 8(5) , e63047. 10.1371/journal.pone.0063047. CMCF-ID Health
Moraes, Trevor F.; Yu, Rong-hua; Strynadka, Natalie C.J.; Schryvers, Anthony B. (2009). Insights into the Bacterial Transferrin Receptor: The Structure of Transferrin-Binding Protein B from Actinobacillus pleuropneumoniae. Molecular Cell 35(4) , 523-533. 10.1016/j.molcel.2009.06.029. CMCF-ID Health
Hou, Jinzhao; Townson, Sharon A.; Kovalchin, Joseph T.; Masci, Allyson; Kiner, Olga et al. (2013). Design of a superior cytokine antagonist for topical ophthalmic use. Proceedings of the National Academy of Sciences of the United States of America 110(10) , 3913-3918. 10.1073/pnas.1217996110. CMCF-ID Health
Abbas, Yazan M.; Pichlmair, Andreas; Górna, Maria W.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2013). Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins. Nature 494(7435) , 60-64. 10.1038/nature11783. CMCF-ID Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. CMCF-BM Health
Langelier, Marie-France; Mirhasan, Manija; Gilbert, Karine; Sverzhinksy, Aleksandr; Furtos, Alexandra et al. (2024). PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Molecular Cell 84(24) , 4758-4773.e6. 10.1016/j.molcel.2024.10.024. CMCF-BM Health
Tian, Yuqing; Worrall, Liam J.; Sim, Lyann; Liu, Feng; Nasseri, Seyed A. et al. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis 14(17) , 13497-13508. 10.1021/acscatal.4c03643. CMCF-BM, CMCF-ID Health
Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. CMCF-BM Health