Publication Beamlines Strategic Pillar
Ali, Mohamed G.; Wahba, Haytham M.; Igelmann, Sebastian; Cyr, Normand; Ferbeyre, Gerardo et al. (2024). Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR. Autophagy . 10.1080/15548627.2024.2353443. CMCF-BM, CMCF-ID Health
Bon, Christopher G.; Grigg, Jason C.; Lee, Jaeyong; Robb, Craig S.; Caveney, Nathanael A. et al. (2024). Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. Journal of Structural Biology 216(2) , 108086. 10.1016/j.jsb.2024.108086. CMCF-BM Health
Callahan, Alex J.; Gandhesiri, Satish; Travaline, Tara L.; Lozano Salazar, Lia; Hanna, Stephanie et al. (2023). Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display. Environmental Science and Technology . 10.26434/chemrxiv-2023-x86xp. CMCF-BM Health
Chen, Sizhu Amelia; Arutyunova, Elena; Lu, Jimmy; Khan, Muhammad Bashir; Rut, Wioletta et al. (2023). SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. ACS Central Science 9(4) , 696-708. 10.1021/acscentsci.3c00054. CMCF-BM Health
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. CMCF-BM, CMCF-ID Health
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. CMCF-BM, CMCF-ID Health
Kuttiyatveetil, Jijin R.A.; Soufari, Heddy; Dasovich, Morgan; Uribe, Isabel R.; Mirhasan, Manija et al. (2022). Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Reports 41(4) , 111529. 10.1016/j.celrep.2022.111529. CMCF-BM Health
Langelier, Marie-France; Mirhasan, Manija; Gilbert, Karine; Sverzhinksy, Aleksandr; Furtos, Alexandra et al. (2024). PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Molecular Cell 84(24) , 4758-4773.e6. 10.1016/j.molcel.2024.10.024. CMCF-BM Health
Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. CMCF-BM Health
Lee, Jaeyong; Kenward, Calem; Worrall, Liam J.; Vuckovic, Marija; Gentile, Francesco et al. (2022). X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nature Communications 13(1) . 10.1038/s41467-022-32854-4. CMCF-BM Health
Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. CMCF-BM Health
Lorente Cobo, Neil; Sibinelli-Sousa, Stephanie; Biboy, Jacob; Vollmer, Waldemar; Bayer-Santos, Ethel et al. (2022). Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold. Journal of Biological Chemistry 298(11) , 102556. 10.1016/j.jbc.2022.102556. CMCF-BM Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. CMCF-BM Health
Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. CMCF-BM Health
Mabanglo, Mark F.; Wong, Keith S.; Barghash, Marim M.; Leung, Elisa; Chuang, Stephanie H.W. et al. (2022). Potent ClpP agonists with anticancer properties bind with improved structural complementarity and alter the mitochondrial N-terminome. Structure . 10.1016/j.str.2022.12.002. CMCF-BM Health