Publication Beamlines Strategic Pillar
Puttick, Jennifer; Vieille, Claire; Song, Seung H.; Fodje, Michel N.; Grochulski, Pawel et al. (2007). Crystallization, preliminary X-ray diffraction and structure analysis ofThermotoga maritimamannitol dehydrogenase. Acta Crystallographica Section F Structural Biology and Crystallization Communications 63(4) , 350-352. 10.1107/s1744309107013097. CMCF-ID Health
Puumala, Emily; Sychantha, David; Lach, Elizabeth; Reeves, Shawn; Nabeela, Sunna et al. (2024). Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity. Cell Chemical Biology . 10.1016/j.chembiol.2024.01.010. [PDB: 8uk6] CMCF-ID Health
Qian, Xinguo; He, Yujiong; Ma, Xinfeng; Fodje, Michel N.; Grochulski, Pawel et al. (2006). Calcium Stiffens Archaeal Rad51 Recombinase from Methanococcus voltae for Homologous Recombination. Journal of Biological Chemistry 281(51) , 39380-39387. 10.1074/jbc.m607785200. [PDB: 2i1q] CMCF-ID Health
Qiu, Liyan; Dhe-Paganon, Sirano (2011). Oligomeric Structure of the MALT1 Tandem Ig-Like Domains. PLoS ONE 6(9) , e23220. 10.1371/journal.pone.0023220. CMCF-ID Health
Qiu, Luping; Levine, Kymberly; Gajiwala, Ketan S.; Cronin, Ciarán N.; Nagata, Asako et al. (2018). Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers. PLoS ONE 13(6) , e0198374. 10.1371/journal.pone.0198374. [PDB: 6cz2, 6cz3] CMCF-ID Health
Quan, Shu; Koldewey, Philipp; Tapley, Tim; Kirsch, Nadine; Ruane, Karen M et al. (2011). Genetic selection designed to stabilize proteins uncovers a chaperone called Spy. Nature Structural and Molecular Biology 18(3) , 262-269. 10.1038/nsmb.2016. [PDB: 3o39] CMCF-ID Health
Quiroz, Ryan V.; Reutershan, Michael H.; Schneider, Sebastian E.; Sloman, David; Lacey, Brian M. et al. (2021). The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer. Journal of Medicinal Chemistry 64(7) , 3911-3939. 10.1021/acs.jmedchem.0c02083. [PDB: 7kib] CMCF-ID Health
Radka, Christopher D.; DeLucas, Lawrence J.; Wilson, Landon S.; Lawrenz, Matthew B.; Perry, Robert D. et al. (2017). Crystal structure ofYersinia pestisvirulence factor YfeA reveals two polyspecific metal-binding sites. Acta Crystallographica Section D: Structural Biology 73(7) , 557-572. 10.1107/s2059798317006349. [PDB: 5uy0, 5uy4, 5uy5, 5uya, 5uyb, 5uyc, 5uyd, 5uye, 5uyf] CMCF-ID Health
Radka, Christopher D.; Labiuk, Shaunivan L.; DeLucas, Lawrence J.; Aller, Stephen G. (2019). Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. Acta Crystallographica Section D: Structural Biology 75(9) . 10.1107/s2059798319010866. [PDB: 6q1d] CMCF-ID Health
Raheem, Izzat T.; Walji, Abbas M.; Klein, Daniel; Sanders, John M.; Powell, David A. et al. (2015). Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry 58(20) , 8154-8165. 10.1021/acs.jmedchem.5b01037. [PDB: 4ztf] CMCF-ID Health
Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] CMCF-ID Health
Rai, Ganesha; Brimacombe, Kyle R.; Mott, Bryan T.; Urban, Daniel J.; Hu, Xin et al. (2017). Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of Medicinal Chemistry 60(22) , 9184-9204. 10.1021/acs.jmedchem.7b00941. [PDB: 5w8h, 5w8j] CMCF-ID Health
Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] CMCF-ID Health
Ramasubramanian, Anusuya; Tennyson, Rachel; Magnay, Maureen; Kathuria, Sagar; Travaline, Tara et al. (2020). Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies 9(4) , 62. 10.3390/antib9040062. [PDB: 7jkb] CMCF-ID Health
Rangarajan, Erumbi S.; Ruane, Karen M.; Proteau, Ariane; Schrag, Joseph D.; Valladares, Ricardo et al. (2011). Structural and enzymatic characterization of NanS (YjhS), a 9-O-Acetyl N-acetylneuraminic acid esterase from Escherichia coli O157:H7. Protein Science 20(7) , 1208-1219. 10.1002/pro.649. [PDB: 3pt5] CMCF-ID Health