Publication Beamlines Strategic Pillar
Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Wan, Honghe; Inghrim, Jennifer A.; Zimmermann, Kurt et al. (2011). Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Bioorganic and Medicinal Chemistry Letters 21(5) , 1425-1428. 10.1016/j.bmcl.2011.01.022. [PDB: 3q32] CMCF-ID Health
Harikrishnan, Lalgudi S.; Gill, Patrice; Kamau, Muthoni G.; Qin, Lan-Ying; Ruan, Zheming et al. (2020). Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists. Bioorganic and Medicinal Chemistry Letters 30(12) , 127204. 10.1016/j.bmcl.2020.127204. [PDB: 6xae] CMCF-ID Health
Han Li; Dorothea Kominos; Jie Zhang; Alla Pritsker; Matthew Davison et al. (2019). Nucleic acids encoding antibodies to Kallidin and des-Arg10-Kallidin and host cells comprising the same. Patent Number: US10465002B2. CMCF-ID Health
Han Li; Dorothea Kominos; Jie Zhang; Alla Pritsker; Matthew Davison et al. (2018). Methods for treating pain using antibodies to Kallidin and des-Arg10-Kallidin. Patent Number: US9879079B2. CMCF-ID Health
Han Li; Dorothea Kominos; Jie Zhang; Alla Pritsker; Matthew Davison et al. (2023). Methods for treating inflammation using antibodies to kallidin and des-arg10-kallidin. Patent Number: US20230399388A1. CMCF-ID Health
Hamaguchi, Hisao; Amano, Yasushi; Moritomo, Ayako; Shirakami, Shohei; Nakajima, Yutaka et al. (2018). Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor. Bioorganic and Medicinal Chemistry 26(18) , 4971-4983. 10.1016/j.bmc.2018.08.005. [PDB: 6aak] CMCF-ID Health
Hallett, Robin M.; Bonfill-Teixidor, Ester; Iurlaro, Raffaella; Arias, Alexandra; Raman, Swetha et al. (2022). Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment. Clinical Cancer Research 29(4) , 791-804. 10.1158/1078-0432.ccr-21-1888. CMCF-ID Health
Halgas, O.; Zarabi, S.F.; Schimmer, A.; Pai, E.F. (2019). Human mitochondrial ClpP in complex with ONC201 (TIC10). Protein Data Bank: 6dl7. CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Saldova, Radka; Muniyappa, Mohankumar; Brade, Lore et al. (2014). Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. Journal of Biological Chemistry 289(24) , 16644-16661. 10.1074/jbc.m113.528224. [PDB: 4m7j, 4m7z, 4m93, 4ma1] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Rodriguez, Teresa; Brade, Lore; Kosma, Paul et al. (2015). Structural Basis for Antibody Recognition of Lipid A. Journal of Biological Chemistry 290(32) , 19629-19640. 10.1074/jbc.m115.657874. [PDB: 4odt, 4odu, 4odv, 4odw, 4z8f, 4z95] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L.; MacKenzie, C. Roger; Caveney, Nathanael et al. (2018). Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry 58(6) , 714-726. 10.1021/acs.biochem.8b00318. [PDB: 6c5h, 6c5i, 6c5j, 6c5k] CMCF-ID Health
Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. [PDB: 5kxb, 5kxc, 5kxd, 5kxe] CMCF-ID Health
Haji-Ghassemi, Omid (2015). Structural characterization of antibodies against lipopolysaccharide antigens: Insights into primary antibody response. Supervisor: Evans, Stephen V.. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/6012. CMCF-ID Health
Haji-Ghassemi, O.; Evans, S.V.; Muller-Loennies, S.; Saldova, R.; Muniyappa, M. et al. (2014). Unliganded 1 crystal structure of S25-26 Fab. Protein Data Bank: 4m7z. CMCF-ID Health
Haji-Ghassemi, O.; Evans, S.V.; Muller-Loennies, S.; Saldova, R.; Muniyappa, M. et al. (2014). Crystal structure of S25-26 in complex with Kdo(2.8)Kdo(2.4)Kdo trisaccharide. Protein Data Bank: 4m7j. CMCF-ID Health