Publication Beamlines Strategic Pillar
Li, Franco K.K.; Rosell, Federico I.; Gale, Robert T.; Simorre, Jean-Pierre; Brown, Eric D. et al. (2020). Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase. Journal of Biological Chemistry 295(9) , 2629-2639. 10.1074/jbc.ra119.011469. [PDB: 6uex, 6uf3, 6uf5, 6uf6] CMCF-ID Health
Alonzo, Diego A.; Chiche-Lapierre, Clarisse; Tarry, Michael J.; Wang, Jimin; Schmeing, T. Martin et al. (2020). Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nature Chemical Biology 16(5) . 10.1038/s41589-020-0481-5. [PDB: 6ulz] CMCF-ID Health
Majdi Yazdi, Mohadeseh; Saran, Sagar; Mrozowich, Tyler; Lehnert, Cheyanne; Patel, Trushar R. et al. (2020). Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase. Journal of Structural Biology 209(1) . 10.1016/j.jsb.2019.107409. [PDB: 6tzu, 6u01] CMCF-BM, CMCF-ID Health
Herrmann, Jonathan; Li, Po-Nan; Jabbarpour, Fatemeh; Chan, Anson C. K.; Rajkovic, Ivan et al. (2019). A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proceedings of the National Academy of Sciences of the United States of America 117(1) , 388-394. 10.1073/pnas.1909798116. [PDB: 6p5t] CMCF-ID Health
Mascle, Xavier H.; Gagnon, Christina; Wahba, Haytham M.; Lussier-Price, Mathieu; Cappadocia, Laurent et al. (2020). Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner. Structure 28(2) . 10.1016/j.str.2019.11.019. [PDB: 6uyo, 6uyp, 6uyq, 6uyr, 6uyu, 6uyz] CMCF-ID Health
Gassaway, Brandon M.; Cardone, Rebecca L.; Padyana, Anil K.; Petersen, Max C.; Judd, Evan T. et al. (2019). Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Reports 29(11) , 3394-3404.e9. 10.1016/j.celrep.2019.11.009. [PDB: 6ech] CMCF-ID Health
Rescourio, Gwenaella; Gonzalez, Ana Z.; Jabri, Salman; Belmontes, Brian; Moody, Gordon et al. (2019). Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere. Journal of Medicinal Chemistry 62(22) , 10258-10271. 10.1021/acs.jmedchem.9b01310. [PDB: 6ud2, 6udi] CMCF-ID Health
McCallum, Matthew; Benlekbir, Samir; Nguyen, Sheryl; Tammam, Stephanie; Rubinstein, John L. et al. (2019). Multiple conformations facilitate PilT function in the type IV pilus. Nature Communications 10(1) . 10.1038/s41467-019-13070-z. [PDB: 6ojy, 6okv] CMCF-ID Health
Tarry, Michael J.; Harmel, Christoph; Taylor, James A.; Marczynski, Gregory T.; Schmeing, T. Martin et al. (2019). Structures of GapR reveal a central channel which could accommodate B-DNA. Scientific Reports 9(1) . 10.1038/s41598-019-52964-2. [PDB: 6ozx, 6ozy, 6ozz] CMCF-ID Health
Reimer, Janice M.; Eivaskhani, Maximilian; Harb, Ingrid; Guarné, Alba; Weigt, Martin et al. (2019). Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science 366(6466) , eaaw4388. 10.1126/science.aaw4388. [PDB: 6mfw, 6mfx, 6mfy, 6mfz] CMCF-ID Health
Wei, Yong; Resetca, Diana; Li, Zhe; Johansson-Åkhe, Isak; Ahlner, Alexandra et al. (2019). Multiple direct interactions of TBP with the MYC oncoprotein. Nature Structural and Molecular Biology 26(11) , 1035-1043. 10.1038/s41594-019-0321-z. [PDB: 6e24] CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Petrilli, Whitney L.; Adam, Gregory C.; Erdmann, Roman S.; Abeywickrema, Pravien; Agnani, Vijayalakshmi et al. (2020). From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chemical Biology 27(1) , 32-40. 10.1016/j.chembiol.2019.10.002. [PDB: 6u36] CMCF-ID Health
Tang, Aimin; Chen, Zhifeng; Cox, Kara S.; Su, Hua-Poo; Callahan, Cheryl et al. (2019). A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein. Nature Communications 10(1) . 10.1038/s41467-019-12137-1. [PDB: 6ous] CMCF-ID Health
Pluvinage, Benjamin; Massel, Patricia M; Burak, Kristyn; Boraston, Alisdair B (2019). Structural and functional analysis of four family 84 glycoside hydrolases from the opportunistic pathogen Clostridium perfringens. Glycobiology 30(1) , 49-57. 10.1093/glycob/cwz069. [PDB: 6pv4] CMCF-BM, CMCF-ID Health