Publication Beamlines Strategic Pillar
Farha, Maya A.; Czarny, Tomasz L.; Myers, Cullen L.; Worrall, Liam J.; French, Shawn et al. (2015). Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proceedings of the National Academy of Sciences of the United States of America 112(35) , 11048-11053. 10.1073/pnas.1511751112. [PDB: 5cqb, 5cqj] CMCF-ID Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Ferri, Elena; Le Thomas, Adrien; Wallweber, Heidi Ackerly; Day, Eric S.; Walters, Benjamin T. et al. (2020). Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature Communications 11(1) . 10.1038/s41467-020-19974-5. [PDB: 6w3b, 6w3c] CMCF-ID Health
Ficko-Blean, Elizabeth; Stuart, Christopher P.; Boraston, Alisdair B. (2011). Structural analysis of CPF_2247, a novel α-amylase from Clostridium perfringens. Proteins: Structure. Function and Bioinformatics 79(10) , 2771-2777. 10.1002/prot.23116. [PDB: 3ren] CMCF-ID Health
Fieldhouse, Robert J.; Jørgensen, René; Lugo, Miguel R.; Merrill, A. Rod (2012). The 1.8 Å Cholix Toxin Crystal Structure in Complex with NAD+ and Evidence for a New Kinetic Model. Journal of Biological Chemistry 287(25) , 21176-21188. 10.1074/jbc.m111.337311. [PDB: 3q9o] CMCF-ID Health
Fodje, Michel; Mundboth, Kiran; Labiuk, Shaunivan; Janzen, Kathryn; Gorin, James et al. (2020). Macromolecular crystallography beamlines at the Canadian Light Source: building on success. Acta Crystallographica Section D: Structural Biology 76(7) . 10.1107/s2059798320007603. CMCF-BM, CMCF-ID Health
Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] CMCF-ID Health
Fong, Desiree H.; Burk, David L.; Blanchet, Jonathan; Yan, Amy Y.; Berghuis, Albert M. et al. (2017). Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure 25(5) , 750-761. 10.1016/j.str.2017.03.007. [PDB: 5igh, 5igi, 5igj, 5igp, 5igr, 5igs, 5igt, 5igu, 5igv, 5igy, 5igz, 5ih0, 5ih1, 5iwu] CMCF-ID Health
Forrester, Taylor J. B.; Ovchinnikova, Olga G.; Li, Zhixiong; Kitova, Elena N.; Nothof, Jeremy T. et al. (2022). The retaining β-Kdo glycosyltransferase WbbB uses a double-displacement mechanism with an intermediate adduct rearrangement step. Nature Communications 13(1) . 10.1038/s41467-022-33988-1. [PDB: 8csb, 8csc, 8csd, 8cse, 8csf] CMCF-BM, CMCF-ID Health
Fortinez, Camille Marie; Bloudoff, Kristjan; Harrigan, Connor; Sharon, Itai; Strauss, Mike et al. (2022). Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nature Communications 13(1) . 10.1038/s41467-022-28221-y. [PDB: 7ly6, 7ly7] CMCF-ID Health
Fowler, Melissa L.; McPhail, Jacob A.; Jenkins, Meredith L.; Masson, Glenn R.; Rutaganira, Florentine U. et al. (2016). Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11. Protein Science 25(4) , 826-839. 10.1002/pro.2879. [PDB: 5c46, 5c4g] CMCF-ID Health
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] CMCF-BM, CMCF-ID Health
Freibert, Sven-A.; Boniecki, Michal T.; Stümpfig, Claudia; Schulz, Vinzent; Krapoth, Nils et al. (2021). N-terminal tyrosine of ISCU2 triggers [2Fe-2S] cluster synthesis by ISCU2 dimerization. Nature Communications 12(1) . 10.1038/s41467-021-27122-w. CMCF-ID Health
Gagarina, Varvara; Bojagora, Anna; Lacdao, Ira Kay; Luthra, Niharika; Pfoh, Roland et al. (2020). Structural Basis of the Interaction Between Ubiquitin Specific Protease 7 and Enhancer of Zeste Homolog 2. Journal of Molecular Biology 432(4) . 10.1016/j.jmb.2019.12.026. [PDB: 6p5l] CMCF-ID Health