Publication Beamlines Strategic Pillar
Ferri, Elena; Le Thomas, Adrien; Wallweber, Heidi Ackerly; Day, Eric S.; Walters, Benjamin T. et al. (2020). Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature Communications 11(1) . 10.1038/s41467-020-19974-5. [PDB: 6w3b, 6w3c] CMCF-ID Health
Scott, William; Lowrance, Brian; Anderson, Alexander C.; Weadge, Joel T. (2020). Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ. PLoS ONE 15(12) , e0242686. 10.1371/journal.pone.0242686. [PDB: 6uje, 6ujf] CMCF-ID Health
Ramasubramanian, Anusuya; Tennyson, Rachel; Magnay, Maureen; Kathuria, Sagar; Travaline, Tara et al. (2020). Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific. Antibodies 9(4) , 62. 10.3390/antib9040062. [PDB: 7jkb] CMCF-ID Health
Hu, Zilun; Wang, Cailan; Glunz, Peter W.; Li, Julia; Cheadle, Nathan L. et al. (2020). Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies. Bioorganic and Medicinal Chemistry Letters 30(21) , 127495. 10.1016/j.bmcl.2020.127495. [PDB: 7jou] CMCF-ID Health
Vance, Tyler D.R.; Ye, Qilu; Conroy, Brigid; Davies, Peter L. (2020). Essential role of calcium in extending RTX adhesins to their target. Journal of Structural Biology: X 4, 100036. 10.1016/j.yjsbx.2020.100036. [PDB: 6xi1, 6xi3] CMCF-ID Health
Majewski, Dorothy D.; Okon, Mark; Heinkel, Florian; Robb, Craig S.; Vuckovic, Marija et al. (2021). Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure 29(2) . 10.1016/j.str.2020.08.006. [PDB: 6xfj] CMCF-BM, CMCF-ID Health
Stirling, Alexander J.; Gilbert, Stephanie E.; Conner, Megan; Mallette, Evan; Kimber, Matthew S. et al. (2020). A Key Glycine in Bacterial Steroid-Degrading Acyl-CoA Dehydrogenases Allows Flavin-Ring Repositioning and Modulates Substrate Side Chain Specificity. Biochemistry 59(42) , 4081-4092. 10.1021/acs.biochem.0c00568. [PDB: 6wy8, 6wy9] CMCF-ID Health
Zhou, Qun; Jaworski, Julie; Zhou, Yanfeng; Valente, Delphine; Cotton, Joanne et al. (2020). Engineered Fc-glycosylation switch to eliminate antibody effector function. mAbs 12(1) , 1814583. 10.1080/19420862.2020.1814583. [PDB: 6x3i] CMCF-ID Health
Dong, Cheng; Nakagawa, Reiko; Oyama, Kyohei; Yamamoto, Yusuke; Zhang, Weilian et al. (2020). Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. eLife 9. 10.7554/elife.58675. [PDB: 6wat, 6wau] CMCF-BM, CMCF-ID Health
McDougall, Matthew; Francisco, Olga; Harder-Viddal, Candice; Roshko, Roy; Heide, Fabian et al. (2019). Proteinaceous Nano container Encapsulate Polycyclic Aromatic Hydrocarbons. Scientific Reports 9(1) . 10.1038/s41598-018-37323-x. CMCF-ID Health
Ye, Qilu; Eves, Robert; Campbell, Robert L.; Davies, Peter L. (2020). Crystal structure of an insect antifreeze protein reveals ordered waters on the ice-binding surface. Biochemical Journal 477(17) . 10.1042/bcj20200539. [PDB: 6xnr] CMCF-ID Health
Gorelik, Alexei; Labriola, Jonathan M.; Illes, Katalin; Nagar, Bhushan (2020). Crystal structure of the nucleotide‐metabolizing enzyme NTPDase4. Protein Science 29(10) . 10.1002/pro.3926. [PDB: 6wg5] CMCF-ID Health
Palte, Rachel L.; Schneider, Sebastian E.; Altman, Michael D.; Hayes, Robert P.; Kawamura, Shuhei et al. (2020). Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5). ACS Medicinal Chemistry Letters 11(9) . 10.1021/acsmedchemlett.9b00525. [PDB: 6uxy] CMCF-ID Health
Stachel, Shawn J.; Ginnetti, Anthony T.; Johnson, Scott A.; Cramer, Paige; Wang, Yi et al. (2020). Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorganic and Medicinal Chemistry Letters 30(17) , 127403. 10.1016/j.bmcl.2020.127403. [PDB: 6x3l, 6x48] CMCF-ID Health
Chung, Chun-wa; Dai, Han; Fernandez, Esther; Tinworth, Christopher P.; Churcher, Ian et al. (2020). Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chemical Biology 15(9) . 10.1021/acschembio.0c00266. [PDB: 6zhc] CMCF-ID Health