Publication Beamlines Strategic Pillar
Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] CMCF-ID Health
Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] CMCF-ID Health
Hehemann, Jan-Hendrik; Smyth, Leo; Yadav, Anuj; Vocadlo, David J.; Boraston, Alisdair B. et al. (2012). Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight into the Degradation (of a Polysaccharide from) Red Seaweeds. Journal of Biological Chemistry 287(17) , 13985-13995. 10.1074/jbc.m112.345645. [PDB: 4ak7] CMCF-ID Health
He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] CMCF-ID Health
Herold, J. Martin; Wigle, Tim J.; Norris, Jacqueline L.; Lam, Robert; Korboukh, Victoria K. et al. (2011). Small-Molecule Ligands of Methyl-Lysine Binding Proteins. Journal of Medicinal Chemistry 54(7) , 2504-2511. 10.1021/jm200045v. [PDB: 3p8h] CMCF-ID Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] CMCF-BM, CMCF-ID Health
Herrmann, Jonathan; Li, Po-Nan; Jabbarpour, Fatemeh; Chan, Anson C. K.; Rajkovic, Ivan et al. (2019). A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proceedings of the National Academy of Sciences of the United States of America 117(1) , 388-394. 10.1073/pnas.1909798116. [PDB: 6p5t] CMCF-ID Health
Hettle, Andrew G.; Vickers, Chelsea; Robb, Craig S.; Liu, Feng; Withers, Stephen G. et al. (2018). The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme. Structure 26(5) , 747-758.e4. 10.1016/j.str.2018.03.012. [PDB: 6b0k] CMCF-ID Health
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara et al. (2016). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 4wi1, 5ifu] CMCF-ID Health
Hewitt, Stephen N.; Choi, Ryan; Kelley, Angela; Crowther, Gregory J.; Napuli, Alberto J. et al. (2011). Expression of proteins inEscherichia colias fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1006-1009. 10.1107/s1744309111022159. [PDB: 3u40] CMCF-ID Health
He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu et al. (2010). Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature 467(7318) , 991-994. 10.1038/nature09408. CMCF-ID Health
He, Yang; Ning, Tingting; Xie, Tingting; Qiu, Qingchuan; Zhang, Liping et al. (2011). Large-scale production of functional human serum albumin from transgenic rice seeds. Proceedings of the National Academy of Sciences of the United States of America 108(47) , 19078-19083. 10.1073/pnas.1109736108. [PDB: 3sqj] CMCF-ID Health
Higgins, Melanie A.; Ficko-Blean, Elizabeth; Meloncelli, Peter J.; Lowary, Todd L.; Boraston, Alisdair B. et al. (2011). The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate-Antigen-Hydrolyzing Enzymes. Journal of Molecular Biology 411(5) , 1017-1036. 10.1016/j.jmb.2011.06.035. [PDB: 2ygm] CMCF-ID Health
Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] CMCF-ID Health
Higgins, Melanie A.; Whitworth, Garrett E.; El Warry, Nahida; Randriantsoa, Mialy; Samain, Eric et al. (2009). Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases. Journal of Biological Chemistry 284(38) , 26161-26173. 10.1074/jbc.m109.024067. CMCF-ID Health