Publication Beamlines Strategic Pillar
White, Brandy; Huh, Ian; Brooks, Cory L. (2019). Structure of a VHH isolated from a naïve phage display library. BMC Research Notes 12(1) . 10.1186/s13104-019-4197-0. [PDB: 6dyx] CMCF-ID Health
Wheatley, Robert W.; Zheng, Ruixiang Blake; Richards, Michele R.; Lowary, Todd L.; Ng, Kenneth K.S. et al. (2012). Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan. Journal of Biological Chemistry 287(33) , 28132-28143. 10.1074/jbc.m112.347484. CMCF-ID Health
Wheatley, Robert W.; Ng, Kenneth K.S.; Kapoor, Manju (2016). Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa. Archives of Biochemistry and Biophysics 590, 125-137. 10.1016/j.abb.2015.11.037. [PDB: 4zty] CMCF-ID Health
Wernimont, Amy K.; Amani, Merhnaz; Qiu, Wei; Pizarro, Juan C.; Artz, Jennifer D. et al. (2010). Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins: Structure. Function and Bioinformatics 79(3) , 803-820. 10.1002/prot.22919. [PDB: 3k21] CMCF-ID Health
Wei, Yong; Xiong, Zi Jian; Li, Jun; Zou, Chunxia; Cairo, Christopher W. et al. (2019). Crystal structures of human lysosomal EPDR1 reveal homology with the superfamily of bacterial lipoprotein transporters. Communications Biology 2(1) . 10.1038/s42003-018-0262-9. [PDB: 6e7o] CMCF-ID Health
Wei, Yong; Resetca, Diana; Li, Zhe; Johansson-Åkhe, Isak; Ahlner, Alexandra et al. (2019). Multiple direct interactions of TBP with the MYC oncoprotein. Nature Structural and Molecular Biology 26(11) , 1035-1043. 10.1038/s41594-019-0321-z. [PDB: 6e24] CMCF-ID Health
Watterson, Scott H.; De Lucca, George V.; Shi, Qing; Langevine, Charles M.; Liu, Qingjie et al. (2016). Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. Journal of Medicinal Chemistry 59(19) , 9173-9200. 10.1021/acs.jmedchem.6b01088. [PDB: 5t18] CMCF-ID Health
Watanabe, Nobuhiko; Clay, Matthew D.; van Belkum, Marco J.; Fan, Chenguang; Vederas, John C. et al. (2011). The Structure of ll-Diaminopimelate Aminotransferase from Chlamydia trachomatis: Implications for Its Broad Substrate Specificity. Journal of Molecular Biology 411(3) , 649-660. 10.1016/j.jmb.2011.06.023. [PDB: 3asb] CMCF-ID Health
Wan, Honghe; Schroeder, Gretchen M.; Hart, Amy C.; Inghrim, Jennifer; Grebinski, James et al. (2015). Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms. ACS Medicinal Chemistry Letters 6(8) , 850-855. 10.1021/acsmedchemlett.5b00226. [PDB: 5cf8] CMCF-ID Health
Wang, Weijun; Mazurkewich, Scott; Kimber, Matthew S.; Seah, Stephen Y.K. (2010). Structural and Kinetic Characterization of 4-Hydroxy-4-methyl-2-oxoglutarate/4-Carboxy-4-hydroxy-2-oxoadipate Aldolase, a Protocatechuate Degradation Enzyme Evolutionarily Convergent with the HpaI and DmpG Pyruvate Aldolases. Journal of Biological Chemistry 285(47) , 36608-36615. 10.1074/jbc.m110.159509. [PDB: 3noj] CMCF-ID Materials
Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] CMCF-ID Health
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health
Wahba, Haytham M.; Lecoq, Lauriane; Stevenson, Michael; Mansour, Ahmed; Cappadocia, Laurent et al. (2016). Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg–Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry 55(7) , 1070-1081. 10.1021/acs.biochem.5b01298. [PDB: 5c17] CMCF-ID Environment
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] CMCF-ID Health
Vu, Binh T.; Dominique, Romyr; Fahr, Bruce J.; Li, Hongju H.; Fry, David C. et al. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.4c00379. [PDB: 9br4] CMCF-ID Health