Publication Beamlines Strategic Pillar
Kumar, Amit; Paul, Marilyn; Panda, Manoranjan; Jayaram, Shruthi; Kalidindi, Narasimharaju et al. (2021). Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology 31(10) . 10.1093/glycob/cwab072. [PDB: 7cxa] CMCF-ID Health
Kundu, Prasun; Semesi, Anthony; Jore, Matthijs M.; Morin, Merribeth J.; Price, Virginia L. et al. (2018). Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45. Nature Communications 9(1) . 10.1038/s41467-018-06742-9. [PDB: 6e62, 6e63, 6e64, 6e65] CMCF-ID Health
Kwan, David H.; Constantinescu, Iren; Chapanian, Rafi; Higgins, Melanie A.; Kötzler, Miriam P et al. (2015). Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution. Journal of the American Chemical Society 137(17) , 5695-5705. 10.1021/ja5116088. [PDB: 4d6c, 4d6d, 4d6e, 4d6g] CMCF-BM, CMCF-ID Health
Labriola, Jonathan M.; Zhou, Yifan; Nagar, Bhushan (2018). Structural Analysis of the Bacterial Effector AvrA Identifies a Critical Helix Involved in Substrate Recognition. Biochemistry 57(33) , 4985-4996. 10.1021/acs.biochem.8b00512. [PDB: 6be0] CMCF-ID Health
Lacbay, Cyrus M.; Waller, Daniel D.; Park, Jaeok; Gómez Palou, Mònica; Vincent, Félix et al. (2018). Unraveling the Prenylation–Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. Journal of Medicinal Chemistry 61(15) , 6904-6917. 10.1021/acs.jmedchem.8b00886. [PDB: 6c56, 6c57] CMCF-ID Health
Langelaan, David N.; Liburd, Janine; Yang, Yidai; Miller, Emily; Chitayat, Seth et al. (2016). Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition. Journal of Biological Chemistry 291(37) , 19607-19617. 10.1074/jbc.m116.746313. [PDB: 5ibw] CMCF-ID Health
Lang, Shenhui; Cressatti, Marisa; Mendoza, Kris E.; Coumoundouros, Chelsea N.; Plater, Samantha M. et al. (2015). YehZYXW of Escherichia coli Is a Low-Affinity, Non-Osmoregulatory Betaine-Specific ABC Transporter. Biochemistry 54(37) , 5735-5747. 10.1021/acs.biochem.5b00274. [PDB: 4wep] CMCF-ID Health
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] CMCF-ID Health
Lau, Kelvin; Van Petegem, Filip (2014). Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain. Nature Communications 5(1) . 10.1038/ncomms6397. [PDB: 4p9i] CMCF-ID Health
Lazareno-Saez, Christelle; Arutyunova, Elena; Coquelle, Nicolas; Lemieux, M. Joanne (2013). Domain Swapping in the Cytoplasmic Domain of the Escherichia coli Rhomboid Protease. Journal of Molecular Biology 425(7) , 1127-1142. 10.1016/j.jmb.2013.01.019. [PDB: 4hdd] CMCF-ID Health
Lee, Ho Jun; Lairson, Luke L.; Rich, Jamie R.; Lameignere, Emilie; Wakarchuk, Warren W. et al. (2011). Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni. Journal of Biological Chemistry 286(41) , 35922-35932. 10.1074/jbc.m111.261172. [PDB: 2x61] CMCF-ID Health
Lee, Ho Jun; Rakić, Bojana; Gilbert, Michel; Wakarchuk, Warren W.; Withers, Stephen G. et al. (2009). Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase OatWY from Neisseria meningitidis. Journal of Biological Chemistry 284(36) , 24501-24511. 10.1074/jbc.m109.006049. [PDB: 2wlg] CMCF-ID Health
Lee, Jaeyong; Taneva, Svetla G.; Holland, Bryan W.; Tieleman, D. Peter; Cornell, Rosemary B. et al. (2014). Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. Journal of Biological Chemistry 289(3) , 1742-1755. 10.1074/jbc.m113.526970. [PDB: 4mvc, 4mvd] CMCF-BM, CMCF-ID Health
Lee, Samuel K.; Shanmughapriya, Santhanam; Mok, Mac C.Y.; Dong, Zhiwei; Tomar, Dhanendra et al. (2016). Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chemical Biology 23(9) , 1157-1169. 10.1016/j.chembiol.2016.07.012. [PDB: 5kue, 5kug, 5kui, 5kuj] CMCF-ID Health
Leighton, T. L.; Mok, M. C.; Junop, M. S.; Howell, P. L.; Burrows, L. L. et al. (2018). Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function. Scientific Reports 8(1) . 10.1038/s41598-018-20925-w. [PDB: 5uvr] CMCF-ID Health