Publication Beamlines Strategic Pillar
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Pemberton, O.A.; Tong, Y.; Nocek, B.; Tang, H.Y.H. (2025). Crystal structure of WRN in complex with compound 43. Protein Data Bank: 9og8. CMCF-ID Health
Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health
Szabla, R.; Junop, M.S.; Wood, K. (2025). Crystal structure of PprA S-F-S tetramer from Deinococcus radiodurans. Protein Data Bank: 9or6. CMCF-ID Health
Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] CMCF-ID Health
Binh Vu; Andrew Good (2023). Uses of p53 x-ray co-crystal structures. Patent Number: US20230024905A1. CMCF-ID Health
Hedda WARDEMANN; Rajagopal Murugan; Tizian Decker; Eiena Levashina; Giulia COSTA et al. (2022). Plasmodium antibodies. Patent Number: US20220396614A1. CMCF-ID Health
Jason Chin; Nicolas HUGUENIN-DEZOT; Mohan MAHESH; Shan Tang; Duy P. Nguyen et al. (2022). Methods and compositions. Patent Number: US20220010296A1. CMCF-ID Health
Joan Seoane Suarez; Judit ANIDO FOLGUEIRA; Robin Matthew Hallett; Peter Edward BAYLISS; Ajitha JEGANATHAN et al. (2021). Methods for improving response to anti-lif antibody treatment in individuals with cancer. Patent Number: US20210253691A1. CMCF-ID Health
Joan Seoane Suarez; Judit ANIDO FOLGUEIRA; Robin Matthew Hallett; Patricia Anne GIBLIN; Jeanne MAGRAM et al. (2021). Combination of lif inhibitors and platinum-based antineoplastic agents for use in treating cancer. Patent Number: US20210187106A1. CMCF-ID Health
Shuaiqi GUO; Ilja VOETS; Peter Davies; Karl Klose (2021). Peptides for use in the treatment of cholera. Patent Number: WO2021010835A1. CMCF-ID Health
Anish SURI; Steven Sheriff; Suzanne Suchard; Aaron YAMNIUK; Stanley Krystek et al. (2020). Nucleic acids encoding antibody polypeptides that antagonize CD40. Patent Number: US10544228B2. CMCF-ID Health