Publication Beamlines Strategic Pillar
Delker, S.L.; Abendroth, J. (2024). Crystal structure of human NUAK1-MARK3 kinase domain chimera bound with small molecule inhibitor #65. Protein Data Bank: 8uoi. CMCF-ID Health
Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] CMCF-ID Health
Fraser, B.J.; Dong, A.; Ilyassov, O.; Seitova, A.; Li, Y. et al. (2024). Crystal structure of TMPRSS11D S368A complexed with its own zymogen activation motif. Protein Data Bank: 9dpf. CMCF-ID Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health
Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] CMCF-ID Health
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). GH5_4 endo-beta(1,3/1,4)-glucanase E331A from Segatella copri in complex with cellotriose. Protein Data Bank: 9bmk. CMCF-ID Health
Cordeiro, R.L.; Golisch, B.; Brumer, H.; Van Petegem, F. (2024). Surface glycan-binding protein A (SGBP-A, SusD-like) from a mixed-linkage beta-glucan utilization locus in Segatella copri in complex with cellopentaose. Protein Data Bank: 9bal. CMCF-ID Health
Golisch, Benedikt; Cordeiro, Rosa Lorizolla; Fraser, Alexander S.C.; Briggs, Jonathon; Stewart, William A. et al. (2024). The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri. Journal of Biological Chemistry 300(9) , 107625. 10.1016/j.jbc.2024.107625. [PDB: 9bal, 9bmk] CMCF-ID Health
Baird, J.; Holliday, M. (2024). Human Bcl-2 (G101V Mutant)/Bcl-xL Chimera Fused to Maltose-Binding Protein. Protein Data Bank: 8vwx. CMCF-ID Health
Aguilar, Eric N.; Sagar, Satish; Murray, Brandy R.; Rajesh, Christabelle; Lei, Eric K. et al. (2024). Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Molecular Cancer Therapeutics 23(6) , 836-853. 10.1158/1535-7163.mct-23-0868. [PDB: 8gkk, 8gkl] CMCF-ID Health
Cygler, M.; Boniecki, M.T. (2024). Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2. Protein Data Bank: 8tvt. CMCF-ID Health
Trofimova, D.; Doubleday, C.; Hunter, B.; Serrano Arevalo, J.; Davison, E. et al. (2024). Crystal structure of the Candida albicans kinesin-8 proximal tail domain. Protein Data Bank: 9crw. CMCF-ID Health
Zheng, X.; Ji, N.; Campbell, V.; Slavin, A.; Zhu, X. et al. (2024). Crystal structure of CRBN with compound 3. Protein Data Bank: 9cuo. CMCF-ID Health
Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] CMCF-ID Health