Publication Beamlines Strategic Pillar
Zhu, Yuao; Yurgelonis, Irina; Noell, Stephen; Yang, Qingyi; Guan, Shunjie et al. (2024). In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Science Advances 10(30) . 10.1126/sciadv.adl4013. [PDB: 9aum] CMCF-ID Health
Zheng, X.; Ji, N.; Campbell, V.; Slavin, A.; Zhu, X. et al. (2024). Crystal structure of CRBN with compound 3. Protein Data Bank: 9cuo. CMCF-ID Health
Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] CMCF-ID Health
Wallweber, H.; Hsu, P.L. (2024). Crystal structure of Para.09 bound to TREM2. Protein Data Bank: 8t59. CMCF-ID Health
Veyron, S.; Cummer, R. (2024). C. difficile Tcdb cysteine protease domain in complex with IP6. Protein Data Bank: 9bja. CMCF-ID Health
Trofimova, D.; Doubleday, C.; Hunter, B.; Serrano Arevalo, J.; Davison, E. et al. (2024). Crystal structure of the Candida albicans kinesin-8 proximal tail domain. Protein Data Bank: 9crw. CMCF-ID Health
Tian, Yuqing; Worrall, Liam J.; Sim, Lyann; Liu, Feng; Nasseri, Seyed A. et al. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis 14(17) , 13497-13508. 10.1021/acscatal.4c03643. [PDB: 9awt, 9ay8, 9ayu] CMCF-BM, CMCF-ID Health
Schroeter, Kurt L.; Rolfe, Nicolas; Forrester, Taylor J.B.; Kimber, Matthew S.; Seah, Stephen Y.K. et al. (2024). Shy is a proteobacterial steroid hydratase which catalyzes steroid side chain degradation without requiring a catalytically inert partner domain. Journal of Biological Chemistry 300(8) , 107509. 10.1016/j.jbc.2024.107509. [PDB: 8vwr] CMCF-ID Health
Schroeter, K.L.; Forrester, T.J.B.; Kimber, M.S.; Seah, S.Y.K. (2024). Structure of steroid hydratase from Comamonas testosteroni. Protein Data Bank: 8vwr. CMCF-ID Health
Sauve, V.; Gehring, K. (2024). Crystal structure of parkin (R0RB):2pUb with activator compound. Protein Data Bank: 8w31. CMCF-ID Health
Sauvé, Véronique; Stefan, Eric; Croteau, Nathalie; Goiran, Thomas; Fakih, Rayan et al. (2024). Activation of parkin by a molecular glue. Nature Communications 15(1) . 10.1038/s41467-024-51889-3. [PDB: 8w31] CMCF-ID Health
Picard, M.-E.; Grenier, J.; Despres, P.C.; Dube, A.K.; Landry, C.R. et al. (2024). Crystal structure of the yeast cytosine deaminase (yCD) M100W mutant. Protein Data Bank: 8vll. CMCF-ID Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Kassardjian, A.; Julien, J.P. (2024). Crystal structure of humanized 44H10 Fab Version 22 in complex with HLA-DR (HLA-DRA*01:01/HLA-DRB1*04:01). Protein Data Bank: 9b7b. CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health