| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G13D, and CypA. Protein Data Bank: 9bg5. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Chen, A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-2, KRAS G12V, and CypA. Protein Data Bank: 9bg4. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS Q61K, and CypA. Protein Data Bank: 9bg3. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Compound-10, KRAS G12V, and CypA. Protein Data Bank: 9bg2. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Bieder, R.; Chen, A.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), NRAS WT, and CypA. Protein Data Bank: 9bg0. |
CMCF-ID |
PDB Deposition |
Health |
| Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-4, KRAS G12C, and CypA. Protein Data Bank: 9bfw. |
CMCF-ID |
PDB Deposition |
Health |
| Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2025). Tri-complex of Compound-19, KRAS G12C, and CypA. Protein Data Bank: 9bfv. |
CMCF-ID |
PDB Deposition |
Health |
| Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. |
CMCF-ID |
PDB Deposition |
Health |
| Hu, Z.; Klupt, K.; Zechel, D.; Jia, Z.; Howe, G. et al. (2025). Crystal Structure of AroC. Protein Data Bank: 9eh6. |
CMCF-ID |
PDB Deposition |
Health |
| Lee, J.; Miranda-Zaragoza, B.; Rodriguez-Almazan, C.; Strynadka, N.C.J. (2025). Thermus thermophilus HB27 laccase (Tth-Lac) mutant with partial deletion of beta-hairpin sequence. Protein Data Bank: 9cpm. |
CMCF-ID |
PDB Deposition |
Health |
| Miranda-Zaragoza, Beatriz; Huerta-Miranda, Guillermo A.; García-García, Wendy I.; Hernández-Álvarez, Elizabeth; Solano-Peralta, Alejandro et al. (2025). Structure-Function Relationship of the β-Hairpin of Thermus thermophilus HB27 Laccase. International Journal of Molecular Sciences 26(2) , 735. 10.3390/ijms26020735. [PDB: 9cpm] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ezekiel, S.; Park, J. (2025). Structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D-C247L) in complex with isopentenyl pyrophosphate. Protein Data Bank: 9csl. |
CMCF-ID |
PDB Deposition |
Health |
| Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] |
CMCF-ID |
Peer-Reviewed Article |
Health |