Publication Beamlines Strategic Pillar
Jha; Vikash Kumar (2011). Structural and functional characterization of catalase HPII of Escherichia coli. Supervisor: Loewen, Peter. Manitoba, Canada: University of Manitoba. http://hdl.handle.net/1993/4829. CMCF-ID Agriculture
Ulaganathan; Thirumalai (2018). Structural studies on enzymes involved in uronic acid polysaccharide degradation. Supervisor: Cygler, Miroslaw. Saskatchewan, Canada: University of Saskatchewan. http://hdl.handle.net/10388/9233. CMCF-BM, CMCF-ID Agriculture
Pfaffen; Stephanie (2014). Iron binding and oxidation by Pseudo-nitzschia multiseries ferritin. Supervisor: Murphy, Michael. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/50303. CMCF-ID Agriculture
Hu, Zhenyu; Klupt, Kody; Zechel, David L.; Jia, Zongchao; Howe, Graeme W. et al. (2025). Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities using Sequence Similarity Networks. ChemBioChem . 10.1002/cbic.202500065. [PDB: 9eh6] CMCF-ID Environment
Hettle, Andrew G.; Hobbs, Joanne K.; Pluvinage, Benjamin; Vickers, Chelsea; Abe, Kento T. et al. (2019). Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species. Communications Biology 2(1) . 10.1038/s42003-019-0721-y. [PDB: 6pnu, 6pop, 6prm, 6psm, 6pt4, 6ptk] CMCF-ID Environment
Nicklisch, Sascha C. T.; Rees, Steven D.; McGrath, Aaron P.; Gökirmak, Tufan; Bonito, Lindsay T. et al. (2016). Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances 2(4) , e1600001-e1600001. 10.1126/sciadv.1600001. [PDB: 4xwk] CMCF-ID Environment
Wahba, Haytham M.; Lecoq, Lauriane; Stevenson, Michael; Mansour, Ahmed; Cappadocia, Laurent et al. (2016). Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg–Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry 55(7) , 1070-1081. 10.1021/acs.biochem.5b01298. [PDB: 5c17] CMCF-ID Environment
Marchetti, Adrian; Parker, Micaela S.; Moccia, Lauren P.; Lin, Ellen O.; Arrieta, Angele L. et al. (2008). Ferritin is used for iron storage in bloom-forming marine pennate diatoms. Nature 457(7228) , 467-470. 10.1038/nature07539. CMCF-ID Environment
Pluvinage, Benjamin; Hehemann, Jan-Hendrik; Boraston, Alisdair B. (2013). Substrate Recognition and Hydrolysis by a Family 50 exo-β-Agarase, Aga50D, from the Marine Bacterium Saccharophagus degradans. Journal of Biological Chemistry 288(39) , 28078-28088. 10.1074/jbc.m113.491068. [PDB: 4bq4, 4bq5] CMCF-ID Environment
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health