Publication Beamlines Strategic Pillar
Aguilar, Eric N.; Sagar, Satish; Murray, Brandy R.; Rajesh, Christabelle; Lei, Eric K. et al. (2024). Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Molecular Cancer Therapeutics 23(6) , 836-853. 10.1158/1535-7163.mct-23-0868. [PDB: 8gkk, 8gkl] CMCF-ID Health
Cygler, M.; Boniecki, M.T. (2024). Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2. Protein Data Bank: 8tvt. CMCF-ID Health
Trofimova, D.; Doubleday, C.; Hunter, B.; Serrano Arevalo, J.; Davison, E. et al. (2024). Crystal structure of the Candida albicans kinesin-8 proximal tail domain. Protein Data Bank: 9crw. CMCF-ID Health
Zheng, X.; Ji, N.; Campbell, V.; Slavin, A.; Zhu, X. et al. (2024). Crystal structure of CRBN with compound 3. Protein Data Bank: 9cuo. CMCF-ID Health
Zheng, Xiaozhang; Ji, Nan; Campbell, Veronica; Slavin, Anthony; Zhu, Xiao et al. (2024). Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c01305. [PDB: 9cuo] CMCF-ID Health
Burke, J.E.; Barlow-Busch, I. (2024). Structure of PIK3CA with covalent inhibitor ALO26. Protein Data Bank: 8twy. CMCF-ID Health
Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 glucuronoyl esterase from Ruminococcus flavefaciens. Protein Data Bank: 8tse. CMCF-ID Health
Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 glucuronoyl esterase from Piromyces rhizinflatus. Protein Data Bank: 8trx. CMCF-ID Health
Gruninger, R.J.; Jones, D.R. (2024). Crystal structure of a CE15 from Fibrobacter succinogenes subsp. succinogenes S85. Protein Data Bank: 8tru. CMCF-ID Health
Gruninger, Robert J.; Kevorkova, Maya; Low, Kristin E.; Jones, Darryl R.; Worrall, Liam et al. (2024). Structural, Biochemical, and Phylogenetic Analysis of Bacterial and Fungal Carbohydrate Esterase Family 15 Glucuronoyl Esterases in the Rumen. Protein Journal 43(4) , 910-922. 10.1007/s10930-024-10221-0. [PDB: 8tru, 8trx, 8tse] CMCF-ID Health
Sauve, V.; Gehring, K. (2024). Crystal structure of parkin (R0RB):2pUb with activator compound. Protein Data Bank: 8w31. CMCF-ID Health
Picard, M.-E.; Grenier, J.; Despres, P.C.; Dube, A.K.; Landry, C.R. et al. (2024). Crystal structure of the yeast cytosine deaminase (yCD) M100W mutant. Protein Data Bank: 8vll. CMCF-ID Health
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] CMCF-BM, CMCF-ID Health
Kassardjian, A.; Julien, J.P. (2024). Crystal structure of humanized 44H10 Fab Version 22 in complex with HLA-DR (HLA-DRA*01:01/HLA-DRB1*04:01). Protein Data Bank: 9b7b. CMCF-ID Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health